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RNAi Experiment: JA:F59C6.9 Ace View of JA:F59C6.9
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F59C6.7 (che-13)
Description of "F59C6.7"  che-13 encodes a novel protein homologous to mammalian IFT57/Hippi (OMIM:606621, protein interactor of Huntingtin-interacting protein 1 that is implicated in neuronal apoptosis in the Huntington disease state); CHE-13 is a proposed component of the intraflagellar transport (IFT) complex B, and is required for the construction and maintenance of cilia on a subset of sensory neurons; in addition, CHE-13 is required for proper localization of OSM-5, a murine polaris homolog, to IFT complex B; CHE-13 is expressed in ciliated sensory neurons including the amphids, phasmids, inner and outer labial neurons, and sensory rays of the male tail, localizing to the cilia base (transition zone) as well as to the axoneme; che-13 expression, like that of ciliogenic genes osm-1, osm-5, osm-6, and che-2, is positively regulated by the DAF-19 RFX-type transcription factor.
KOG Annotation  Huntingtin interacting protein 1 (Hip1) interactor Hippi
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:10507192..10508275)
Transcript overlap: 770 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 646
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F59C6.7" Links  Wormbase NCBI
JA:F59C6.9 Phenotypes Help with Phenotypes
Phenotype  WT
JA:F59C6.9 Experiment Details Ace View
Laboratory  JA
RNAi Reagent & Type  sjj_F59C6.9 (PCR_reagent)
Reference  Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...."
Date  2000-11-16
Gene Plot of F59C6.7 Browse using GBrowse
Gene Graph