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RNAi Experiment: JA:R05D11.3 Ace View of JA:R05D11.3
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  R05D11.3 (ran-4)
Description of "R05D11.3"  ran-4 encodes a ortholog of NUCLEAR TRANSPORT FACTOR 2 (NTF2) from S. cerevisiae and metazoa, which is predicted to interact with nucleoporins and to promote transport of RAN-1(+GDP) into the nucleus; RAN-4/NTF2 proteins are paralogous to the N-terminal domain of RasGAP SH3 binding proteins such as Drosophila RASPUTIN, and to delta-5-3-ketosteroid isomerases, while having no homology to Ran proteins per se; RAN-4 is essential for early embryogenesis; in mass RNAi assays, ran-4 is needed for embryonic viability, normally rapid growth, fertility, and normal pronuclear envelopes in the embryo.
KOG Annotation  Nuclear transport factor 2
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:8590897..8591819)
Transcript overlap: 487 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 403
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "R05D11.3" Links  Wormbase NCBI
JA:R05D11.3 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 100 %
Larval  Gro
Adult  Ste brood size range (1 out of 5)
Phenotype  Pna <200 cells
Movies/Stacks/Images  /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif /static/images/movie.gif Help
JA:R05D11.3 Experiment Details Ace View
Laboratory  JA
RNAi Reagent & Type  sjj_R05D11.3 (PCR_reagent)
Remark  P1 division late
Reference  Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...."
Date  2000-11-16
Gene Plot of R05D11.3 Browse using GBrowse
Gene Graph