RNAi Experiment: JA:R06C7.7 |
Ace View of JA:R06C7.7
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Genes Inhibited |
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Gene Inhibited |
R06C7.7 (lin-61) |
Description of "R06C7.7" |
lin-61 encodes a protein that contains mbt repeats and has similarity to the Drosophila Polycomb group protein Sex Comb on Midleg and human protein H-l-(3)mbl-like; by homology, LIN-61 is predicted to function as part of a transcriptional regulatory complex that may play a role in transcriptional repression during development; loss of lin-61 activity via RNAi and forward mutations indicates that LIN-61 is required for: 1) genome stability in the soma and germline, and 2) postembryonic developmental processes such as vulval development, in which lin-61 acts as a class B synthetic multivulval (SynMuv) gene. |
KOG Annotation  |
Polycomb group protein SCM/L(3)MBT (tumor-supressor in Drosophila and humans)
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (I:7249125..7250306)
Transcript overlap: 1029 nt |
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Sliding Window |
Raw score: 966
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "R06C7.7" Links |
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JA:R06C7.7 Phenotypes |
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Phenotype |
WT
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JA:R06C7.7 Experiment Details |
Ace View |
Laboratory |
JA |
RNAi Reagent & Type |
sjj_R06C7.7 (PCR_reagent) |
Reference |
Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...." |
Date |
2000-11-16 |
Gene Plot of R06C7.7 |
Browse using GBrowse
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