RNAi Experiment: JA:R10A10.2 |
Ace View of JA:R10A10.2
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Genes Inhibited |
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Gene Inhibited |
R10A10.2 (rbx-2) |
Description of "R10A10.2" |
The R10A10.2 gene encodes an ortholog of the mammalian zinc RING finger protein SAG, which protects cells from apoptosis induced by redox agents and is a component of ubiquitin-ligase (E3) complexes; mammalian SAG binds to the yeast Cul1 protein, complements the lethality of a mutation in yeast Sag, and (when bound to yeast Cul1) has ubiquitin ligase activity and promotes poly-ubiquitination of E2/Cdc34. |
KOG Annotation  |
SCF ubiquitin ligase, Rbx1 component
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (I:6420396..6421905)
Transcript overlap: 467 nt |
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Sliding Window |
Raw score: 404
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "R10A10.2" Links |
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JA:R10A10.2 Phenotypes |
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Phenotype |
WT
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JA:R10A10.2 Experiment Details |
Ace View |
Laboratory |
JA |
RNAi Reagent & Type |
sjj_R10A10.2 (PCR_reagent) |
Reference |
Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...." |
Date |
2000-11-16 |
Gene Plot of R10A10.2 |
Browse using GBrowse
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