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RNAi Experiment: JA:R10E11.1 Ace View of JA:R10E11.1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  R10E11.1 (cbp-1)
Description of "R10E11.1"  cbp-1 encodes a homolog of the mammalian transcriptional cofactors CBP (OMIM:600140) and p300 (E1A-BINDING PROTEIN, 300-KD; OMIM:602700) that have been shown to possess histone acetyltransferase activity, and which, when mutated, lead to Rubinstein-Taybi syndrome (OMIM:180849) and colorectal cancer (OMIM:114500); at least one splicing form of CBP-1 exhibits histone acetyltransferase (HAT) activity in vitro and has a glutamine/asparagine-rich domain; CBP-1 is required during embryogenesis for differentiation of all non-neuronal somatic cell types; CBP-1 is expressed very early in embryogenesis, suggesting that it may interact with maternally provided transcription factors, such as SKN-1, to specific developmental fates.
KOG Annotation  CREB binding protein/P300 and related TAZ Zn-finger proteins
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:9770407..9771580)
Transcript overlap: 1174 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 1153
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "R10E11.1" Links  Wormbase NCBI
JA:R10E11.1 Phenotypes Help with Phenotypes
Adult  Sck
Ste
JA:R10E11.1 Experiment Details Ace View
Laboratory  JA
RNAi Reagent & Type  sjj_R10E11.1 (PCR_reagent)
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Date  2003-1-10
Gene Plot of R10E11.1 Browse using GBrowse
Gene Graph