Link to R13H8.1fLink to R13H8.1dLink to R13H8.1cLink to R13H8.1bLink to R13H8.1e.2Link to R13H8.1aLink to R13H8.1e.1RNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
RNAi Experiment: JA:R13H8.2 Ace View of JA:R13H8.2
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  R13H8.1 (daf-16)
Description of "R13H8.1"  daf-16 encodes a transcription factor of the HNF-3/forkhead family (orthologous to mammalian AFX, FKHR, and FKHRL1) that acts in an insulin-mediated pathway to affect dauer formation, and that also affects life span and reproduction; DAF-16 can interact with CBP-1 in vitro, and interacts genetically both with other genes in the insulin signaling and with the nuclear hormone receptor DAF-12; daf-16 is broadly expressed in most if not all cells (though expression in the pharynx and in the somatic gonad differ for the two isoforms); DAF-16 is homologous to human FORKHEAD BOX O1A (FOXO1A), which when mutated leads to rhabdomyosarcoma (OMIM:136533).
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:10762888..10765350)
Transcript overlap: 784 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 616
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "R13H8.1" Links  Wormbase NCBI
JA:R13H8.2 Phenotypes Help with Phenotypes
Phenotype  WT
JA:R13H8.2 Experiment Details Ace View
Laboratory  JA
RNAi Reagent & Type  sjj_R13H8.2 (PCR_reagent)
Reference  Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...."
Date  2000-11-16
Gene Plot of R13H8.1 Browse using GBrowse
Gene Graph