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RNAi Experiment: JA:T05F1.6 Ace View of JA:T05F1.6
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T05F1.6 (hsr-9)
Description of "T05F1.6"  hsr-9 encodes a protein containing a BRCT (BRCA 1 C terminus) domain that is found in proteins that regulate the cell cycle checkpoint in response to DNA damage; HSR-9 activity is required for a normal response to DNA damage caused by gamma-irradiation; loss of HSR-9 function via RNA-mediated interference after gamma-irradiation results in defects in mitotic cell cycle arrest, reduction of apoptosis of pachytene nuclei, and radiation sensitivity of progeny; the expression pattern and subcellular localization of HSR-9 are not yet known.
KOG Annotation  DNA damage checkpoint protein RHP9/CRB2/53BP1
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:9627210..9628386)
Transcript overlap: 1130 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 1103
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "T05F1.6" Links  Wormbase NCBI
JA:T05F1.6 Phenotypes Help with Phenotypes
Phenotype  WT
JA:T05F1.6 Experiment Details Ace View
Laboratory  JA
RNAi Reagent & Type  sjj_T05F1.6 (PCR_reagent)
Reference  Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...."
Date  2000-11-16
Gene Plot of T05F1.6 Browse using GBrowse
Gene Graph