RNAi Card Page

RNAi Experiment: JA:T13F2.11

Genes Inhibited

Gene Inhibited

Description of "T13F2.11"

msp-78 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

ePCR	Status: Unique_ePCR (IV:9769712..9770700) Transcript overlap: 430 nt
Sliding Window	Raw score: 388 Relative score: 1 (This gene has the best score for this RNAi reagent) Specificity index: 0.11
Wormbase (BLAST)	RNAi primary

External "T13F2.11" Links

Gene Inhibited

Y59E9AR.7

Description of "Y59E9AR.7"

Associated GO Term : structural molecule activity

Evidence for Inhibition

Sliding Window	Raw score: 77 Specificity index: 0.022
Wormbase (BLAST)	RNAi secondary

External "Y59E9AR.7" Links

Gene Inhibited

R05F9.3 (msp-32)

Description of "R05F9.3"

msp-32 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-32 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the msp family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 59
Wormbase (BLAST)	RNAi secondary

External "R05F9.3" Links

Gene Inhibited

K07F5.2 (msp-10)

Description of "K07F5.2"

msp-10 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 220 Relative score: 0.567 (Best raw score= for Gene ) Specificity index: 0.062
Wormbase (BLAST)	RNAi primary

External "K07F5.2" Links

Gene Inhibited

C09B9.6 (msp-55)

Description of "C09B9.6"

msp-55 encodes a member of the major sperm protein family.

Evidence for Inhibition

Sliding Window	Raw score: 81 Relative score: 0.209 (Best raw score= for Gene ) Specificity index: 0.023
Wormbase (BLAST)	RNAi secondary

External "C09B9.6" Links

Gene Inhibited

K07F5.1 (msp-81)

Description of "K07F5.1"

msp-81 encodes a member of the major sperm protein family.

Evidence for Inhibition

Sliding Window	Raw score: 222 Relative score: 0.572 (Best raw score= for Gene ) Specificity index: 0.063
Wormbase (BLAST)	RNAi primary

External "K07F5.1" Links

Gene Inhibited

F36H12.7 (msp-19)

Description of "F36H12.7"

msp-19 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-19 has a homolog in C. briggsae as predicted by the Wobble Aware Bulk Aligner (WABA); the msp gene family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 70 Relative score: 0.18 (Best raw score= for Gene ) Specificity index: 0.02
Wormbase (BLAST)	RNAi secondary

External "F36H12.7" Links

Gene Inhibited

Y59E9AR.1

Description of "Y59E9AR.1"

Associated GO Term : structural molecule activity

Evidence for Inhibition

Sliding Window	Raw score: 77 Relative score: 0.198 (Best raw score= for Gene ) Specificity index: 0.022
Wormbase (BLAST)	RNAi secondary

External "Y59E9AR.1" Links

Gene Inhibited

R13H9.2 (msp-57)

Description of "R13H9.2"

msp-57 encodes a member of the major sperm protein family.

Evidence for Inhibition

Sliding Window	Raw score: 87 Relative score: 0.224 (Best raw score= for Gene ) Specificity index: 0.025
Wormbase (BLAST)	RNAi secondary

External "R13H9.2" Links

Gene Inhibited

K08F4.8 (msp-38)

Description of "K08F4.8"

msp-38 encodes a member of the major sperm protein family; msp-38 has a C. briggsae homolog as predicted by the Wobble Bulk Aware Bulk Aligner (WABA).

Evidence for Inhibition

Sliding Window	Raw score: 191 Relative score: 0.492 (Best raw score= for Gene ) Specificity index: 0.054
Wormbase (BLAST)	RNAi secondary

External "K08F4.8" Links

Gene Inhibited

ZK354.5 (msp-51)

Description of "ZK354.5"

msp-51 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-51 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 76 Relative score: 0.196 (Best raw score= for Gene ) Specificity index: 0.022
Wormbase (BLAST)	RNAi secondary

External "ZK354.5" Links

Gene Inhibited

ZK354.10 (msp-58)

Description of "ZK354.10"

msp-58 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 71 Relative score: 0.183 (Best raw score= for Gene ) Specificity index: 0.02
Wormbase (BLAST)	RNAi secondary

External "ZK354.10" Links

Gene Inhibited

T13F2.10 (msp-79)

Description of "T13F2.10"

msp-79 encodes a member of the major sperm protein family.

Evidence for Inhibition

Sliding Window	Raw score: 281 Relative score: 0.724 (Best raw score= for Gene ) Specificity index: 0.08
Wormbase (BLAST)	RNAi primary

External "T13F2.10" Links

Gene Inhibited

F32B6.6 (msp-77)

Description of "F32B6.6"

msp-77 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 224 Relative score: 0.577 (Best raw score= for Gene ) Specificity index: 0.064
Wormbase (BLAST)	RNAi primary

External "F32B6.6" Links

Gene Inhibited

F58A6.8 (msp-45)

Description of "F58A6.8"

msp-45 encodes a member of the major sperm protein family.

Evidence for Inhibition

Sliding Window	Raw score: 66 Relative score: 0.17 (Best raw score= for Gene ) Specificity index: 0.019
Wormbase (BLAST)	RNAi secondary

External "F58A6.8" Links

Gene Inhibited

R13H9.4 (msp-53)

Description of "R13H9.4"

msp-53 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-53 has a C. briggsae homolog as identified by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 67 Specificity index: 0.019
Wormbase (BLAST)	RNAi secondary

External "R13H9.4" Links

Gene Inhibited

ZK354.4 (msp-113)

Description of "ZK354.4"

msp-113 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-113 has a C. briggsae homolog as detected by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; the msp-113 promoter region contains two conserved cis elements that are recognition sites for elt-1, a gene that encodes a homolog of the vertebrate GATA transcription factor family; this suggests that a MSP protein is a potential target for ELT-1 in the germ-line; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 83 Relative score: 0.214 (Best raw score= for Gene ) Specificity index: 0.024
Wormbase (BLAST)	RNAi secondary

External "ZK354.4" Links

Gene Inhibited

R05F9.8 (msp-33)

Description of "R05F9.8"

msp-33 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-33 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 59
Wormbase (BLAST)	RNAi secondary

External "R05F9.8" Links

Gene Inhibited

ZK354.11 (msp-59)

Description of "ZK354.11"

msp-59 encodes a member of the major sperm protein family.

Evidence for Inhibition

Sliding Window	Raw score: 93 Relative score: 0.24 (Best raw score= for Gene ) Specificity index: 0.026
Wormbase (BLAST)	RNAi secondary

External "ZK354.11" Links

Gene Inhibited

C04G2.4 (msp-36)

Description of "C04G2.4"

msp-36 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family comprises of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSP is involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP assembles into fibrous networks that drives movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 167 Relative score: 0.43 (Best raw score= for Gene ) Specificity index: 0.047
Wormbase (BLAST)	RNAi secondary

External "C04G2.4" Links

Gene Inhibited

ZK1251.6 (msp-76)

Description of "ZK1251.6"

msp-76 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 182 Relative score: 0.469 (Best raw score= for Gene ) Specificity index: 0.052
Wormbase (BLAST)	RNAi secondary

External "ZK1251.6" Links

Gene Inhibited

ZK354.1 (msp-65)

Description of "ZK354.1"

msp-65 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 89 Relative score: 0.229 (Best raw score= for Gene ) Specificity index: 0.025
Wormbase (BLAST)	RNAi secondary

External "ZK354.1" Links

Gene Inhibited

C04G2.3

Evidence for Inhibition

Sliding Window	Raw score: 228 Relative score: 0.588 (Best raw score= for Gene ) Specificity index: 0.065
Wormbase (BLAST)	RNAi primary

External "C04G2.3" Links

Gene Inhibited

K07F5.3 (msp-56)

Description of "K07F5.3"

msp-56 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 274 Relative score: 0.706 (Best raw score= for Gene ) Specificity index: 0.078
Wormbase (BLAST)	RNAi primary

External "K07F5.3" Links

Gene Inhibited

F36H12.6 (msp-52)

Description of "F36H12.6"

msp-52 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 67 Relative score: 0.173 (Best raw score= for Gene ) Specificity index: 0.019
Wormbase (BLAST)	RNAi secondary

External "F36H12.6" Links

Gene Inhibited

F59A6.8 (msp-71)

Description of "F59A6.8"

msp-71 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 62 Relative score: 0.16 (Best raw score= for Gene ) Specificity index: 0.018
Wormbase (BLAST)	RNAi secondary

External "F59A6.8" Links

Gene Inhibited

R05F9.13 (msp-31)

Description of "R05F9.13"

msp-31 encodes a member of the major sperm protein family; msp-31 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); expression is enriched in sperm.

Evidence for Inhibition