RNAi Experiment: JA:T13F2.11 |
Ace View of JA:T13F2.11
|
Genes Inhibited |
 |
Gene Inhibited |
T13F2.11 (msp-78) |
Description of "T13F2.11" |
msp-78 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (IV:9769712..9770700)
Transcript overlap: 430 nt |
|
Sliding Window |
Raw score: 388
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.11 |
Wormbase (BLAST) |
RNAi primary |
|
External "T13F2.11" Links |
 |
Gene Inhibited |
Y59E9AR.7 |
Description of "Y59E9AR.7" |
Associated GO Term : structural molecule activity |
Evidence for Inhibition |
Sliding Window |
Raw score: 77
Specificity index: 0.022 |
Wormbase (BLAST) |
RNAi secondary |
|
External "Y59E9AR.7" Links |
 |
Gene Inhibited |
R05F9.3 (msp-32) |
Description of "R05F9.3" |
msp-32 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-32 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the msp family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 59 |
Wormbase (BLAST) |
RNAi secondary |
|
External "R05F9.3" Links |
 |
Gene Inhibited |
K07F5.2 (msp-10) |
Description of "K07F5.2" |
msp-10 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 220
Relative score: 0.567 (Best raw score= for Gene )
Specificity index: 0.062 |
Wormbase (BLAST) |
RNAi primary |
|
External "K07F5.2" Links |
 |
Gene Inhibited |
C09B9.6 (msp-55) |
Description of "C09B9.6" |
msp-55 encodes a member of the major sperm protein family. |
Evidence for Inhibition |
Sliding Window |
Raw score: 81
Relative score: 0.209 (Best raw score= for Gene )
Specificity index: 0.023 |
Wormbase (BLAST) |
RNAi secondary |
|
External "C09B9.6" Links |
 |
Gene Inhibited |
K07F5.1 (msp-81) |
Description of "K07F5.1" |
msp-81 encodes a member of the major sperm protein family. |
Evidence for Inhibition |
Sliding Window |
Raw score: 222
Relative score: 0.572 (Best raw score= for Gene )
Specificity index: 0.063 |
Wormbase (BLAST) |
RNAi primary |
|
External "K07F5.1" Links |
 |
Gene Inhibited |
F36H12.7 (msp-19) |
Description of "F36H12.7" |
msp-19 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-19 has a homolog in C. briggsae as predicted by the Wobble Aware Bulk Aligner (WABA); the msp gene family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 70
Relative score: 0.18 (Best raw score= for Gene )
Specificity index: 0.02 |
Wormbase (BLAST) |
RNAi secondary |
|
External "F36H12.7" Links |
 |
Gene Inhibited |
Y59E9AR.1 |
Description of "Y59E9AR.1" |
Associated GO Term : structural molecule activity |
Evidence for Inhibition |
Sliding Window |
Raw score: 77
Relative score: 0.198 (Best raw score= for Gene )
Specificity index: 0.022 |
Wormbase (BLAST) |
RNAi secondary |
|
External "Y59E9AR.1" Links |
 |
Gene Inhibited |
R13H9.2 (msp-57) |
Description of "R13H9.2" |
msp-57 encodes a member of the major sperm protein family. |
Evidence for Inhibition |
Sliding Window |
Raw score: 87
Relative score: 0.224 (Best raw score= for Gene )
Specificity index: 0.025 |
Wormbase (BLAST) |
RNAi secondary |
|
External "R13H9.2" Links |
 |
Gene Inhibited |
K08F4.8 (msp-38) |
Description of "K08F4.8" |
msp-38 encodes a member of the major sperm protein family; msp-38 has a C. briggsae homolog as predicted by the Wobble Bulk Aware Bulk Aligner (WABA). |
Evidence for Inhibition |
Sliding Window |
Raw score: 191
Relative score: 0.492 (Best raw score= for Gene )
Specificity index: 0.054 |
Wormbase (BLAST) |
RNAi secondary |
|
External "K08F4.8" Links |
 |
Gene Inhibited |
ZK354.5 (msp-51) |
Description of "ZK354.5" |
msp-51 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-51 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 76
Relative score: 0.196 (Best raw score= for Gene )
Specificity index: 0.022 |
Wormbase (BLAST) |
RNAi secondary |
|
External "ZK354.5" Links |
 |
Gene Inhibited |
ZK354.10 (msp-58) |
Description of "ZK354.10" |
msp-58 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 71
Relative score: 0.183 (Best raw score= for Gene )
Specificity index: 0.02 |
Wormbase (BLAST) |
RNAi secondary |
|
External "ZK354.10" Links |
 |
Gene Inhibited |
T13F2.10 (msp-79) |
Description of "T13F2.10" |
msp-79 encodes a member of the major sperm protein family. |
Evidence for Inhibition |
Sliding Window |
Raw score: 281
Relative score: 0.724 (Best raw score= for Gene )
Specificity index: 0.08 |
Wormbase (BLAST) |
RNAi primary |
|
External "T13F2.10" Links |
 |
Gene Inhibited |
F32B6.6 (msp-77) |
Description of "F32B6.6" |
msp-77 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 224
Relative score: 0.577 (Best raw score= for Gene )
Specificity index: 0.064 |
Wormbase (BLAST) |
RNAi primary |
|
External "F32B6.6" Links |
 |
Gene Inhibited |
F58A6.8 (msp-45) |
Description of "F58A6.8" |
msp-45 encodes a member of the major sperm protein family. |
Evidence for Inhibition |
Sliding Window |
Raw score: 66
Relative score: 0.17 (Best raw score= for Gene )
Specificity index: 0.019 |
Wormbase (BLAST) |
RNAi secondary |
|
External "F58A6.8" Links |
 |
Gene Inhibited |
R13H9.4 (msp-53) |
Description of "R13H9.4" |
msp-53 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-53 has a C. briggsae homolog as identified by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 67
Specificity index: 0.019 |
Wormbase (BLAST) |
RNAi secondary |
|
External "R13H9.4" Links |
 |
Gene Inhibited |
ZK354.4 (msp-113) |
Description of "ZK354.4" |
msp-113 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-113 has a C. briggsae homolog as detected by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; the msp-113 promoter region contains two conserved cis elements that are recognition sites for elt-1, a gene that encodes a homolog of the vertebrate GATA transcription factor family; this suggests that a MSP protein is a potential target for ELT-1 in the germ-line; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 83
Relative score: 0.214 (Best raw score= for Gene )
Specificity index: 0.024 |
Wormbase (BLAST) |
RNAi secondary |
|
External "ZK354.4" Links |
 |
Gene Inhibited |
R05F9.8 (msp-33) |
Description of "R05F9.8" |
msp-33 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-33 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 59 |
Wormbase (BLAST) |
RNAi secondary |
|
External "R05F9.8" Links |
 |
Gene Inhibited |
ZK354.11 (msp-59) |
Description of "ZK354.11" |
msp-59 encodes a member of the major sperm protein family. |
Evidence for Inhibition |
Sliding Window |
Raw score: 93
Relative score: 0.24 (Best raw score= for Gene )
Specificity index: 0.026 |
Wormbase (BLAST) |
RNAi secondary |
|
External "ZK354.11" Links |
 |
Gene Inhibited |
C04G2.4 (msp-36) |
Description of "C04G2.4" |
msp-36 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family comprises of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSP is involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP assembles into fibrous networks that drives movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 167
Relative score: 0.43 (Best raw score= for Gene )
Specificity index: 0.047 |
Wormbase (BLAST) |
RNAi secondary |
|
External "C04G2.4" Links |
 |
Gene Inhibited |
ZK1251.6 (msp-76) |
Description of "ZK1251.6" |
msp-76 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 182
Relative score: 0.469 (Best raw score= for Gene )
Specificity index: 0.052 |
Wormbase (BLAST) |
RNAi secondary |
|
External "ZK1251.6" Links |
 |
Gene Inhibited |
ZK354.1 (msp-65) |
Description of "ZK354.1" |
msp-65 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 89
Relative score: 0.229 (Best raw score= for Gene )
Specificity index: 0.025 |
Wormbase (BLAST) |
RNAi secondary |
|
External "ZK354.1" Links |
 |
Gene Inhibited |
C04G2.3 |
Evidence for Inhibition |
Sliding Window |
Raw score: 228
Relative score: 0.588 (Best raw score= for Gene )
Specificity index: 0.065 |
Wormbase (BLAST) |
RNAi primary |
|
External "C04G2.3" Links |
 |
Gene Inhibited |
K07F5.3 (msp-56) |
Description of "K07F5.3" |
msp-56 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 274
Relative score: 0.706 (Best raw score= for Gene )
Specificity index: 0.078 |
Wormbase (BLAST) |
RNAi primary |
|
External "K07F5.3" Links |
 |
Gene Inhibited |
F36H12.6 (msp-52) |
Description of "F36H12.6" |
msp-52 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 67
Relative score: 0.173 (Best raw score= for Gene )
Specificity index: 0.019 |
Wormbase (BLAST) |
RNAi secondary |
|
External "F36H12.6" Links |
 |
Gene Inhibited |
F59A6.8 (msp-71) |
Description of "F59A6.8" |
msp-71 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 62
Relative score: 0.16 (Best raw score= for Gene )
Specificity index: 0.018 |
Wormbase (BLAST) |
RNAi secondary |
|
External "F59A6.8" Links |
 |
Gene Inhibited |
R05F9.13 (msp-31) |
Description of "R05F9.13" |
msp-31 encodes a member of the major sperm protein family; msp-31 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); expression is enriched in sperm. |
Evidence for Inhibition |
Sliding Window |
Raw score: 80
Relative score: 0.206 (Best raw score= for Gene )
Specificity index: 0.023 |
Wormbase (BLAST) |
RNAi secondary |
|
External "R05F9.13" Links |
 |
JA:T13F2.11 Phenotypes |
|
 |
Phenotype |
WT
|
JA:T13F2.11 Experiment Details |
Ace View |
Laboratory |
JA |
RNAi Reagent & Type |
sjj_T13F2.11 (PCR_reagent) |
Reference |
Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." |
Date |
2003-1-10 |
Gene Plot of Y59E9AR.7 |
Browse using GBrowse
|
 |
Gene Plot of R05F9.3 |
Browse using GBrowse
|
 |
Gene Plot of K07F5.2 |
Browse using GBrowse
|
 |
Gene Plot of C09B9.6 |
Browse using GBrowse
|
 |
Gene Plot of K07F5.1 |
Browse using GBrowse
|
 |
Gene Plot of K08F4.8 |
Browse using GBrowse
|
 |
Gene Plot of R13H9.2 |
Browse using GBrowse
|
 |
Gene Plot of F36H12.7 |
Browse using GBrowse
|
 |
Gene Plot of Y59E9AR.1 |
Browse using GBrowse
|
 |
Gene Plot of F58A6.8 |
Browse using GBrowse
|
 |
Gene Plot of F32B6.6 |
Browse using GBrowse
|
 |
Gene Plot of T13F2.10 |
Browse using GBrowse
|
 |
Gene Plot of ZK354.10 |
Browse using GBrowse
|
 |
Gene Plot of ZK354.5 |
Browse using GBrowse
|
 |
Gene Plot of R05F9.8 |
Browse using GBrowse
|
 |
Gene Plot of ZK354.4 |
Browse using GBrowse
|
 |
Gene Plot of R13H9.4 |
Browse using GBrowse
|
 |
Gene Plot of ZK354.11 |
Browse using GBrowse
|
 |
Gene Plot of T13F2.11 |
Browse using GBrowse
|
 |
Gene Plot of C04G2.4 |
Browse using GBrowse
|
 |
Gene Plot of ZK1251.6 |
Browse using GBrowse
|
 |
Gene Plot of ZK354.1 |
Browse using GBrowse
|
 |
Gene Plot of C04G2.3 |
Browse using GBrowse
|
 |
Gene Plot of K07F5.3 |
Browse using GBrowse
|
 |
Gene Plot of F36H12.6 |
Browse using GBrowse
|
 |
Gene Plot of R05F9.13 |
Browse using GBrowse
|
 |
Gene Plot of F59A6.8 |
Browse using GBrowse
|
 |