RNAi Card Page

RNAi Experiment: JA:T15B7.3

Ace View of JA:T15B7.3

Genes Inhibited

Gene Inhibited

T15B7.3 (col-143)

Description of "T15B7.3"

Associated GO Term : structural constituent of cuticle

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

ePCR	Status: Unique_ePCR (V:6838302..6839272) Transcript overlap: 921 nt
Sliding Window	Raw score: 858 Relative score: 0.818 (Best raw score= for Gene ) Specificity index: 0.228
Wormbase (BLAST)	RNAi primary

External "T15B7.3" Links

Gene Inhibited

T28C6.4 (col-117)

Description of "T28C6.4"

Associated GO Term : structural constituent of cuticle

Evidence for Inhibition

Sliding Window

Raw score: 88
Specificity index: 0.023

External "T28C6.4" Links

Gene Inhibited

H06A10.2 (col-185)

Description of "H06A10.2"

Associated GO Term : structural constituent of cuticle

Evidence for Inhibition

Sliding Window

Raw score: 194
Relative score: 0.185 (Best raw score= for Gene )
Specificity index: 0.051

External "H06A10.2" Links

Gene Inhibited

T13B5.4 (col-40)

Description of "T13B5.4"

col-40 encodes a cuticle collagen protein that belongs to the col-6 cuticle collagen family; col-40 transcript is present in L1 larvae and at the L2d-dauer molt.

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 121
Specificity index: 0.032

External "T13B5.4" Links

Gene Inhibited

T28C6.6 (col-3)

Description of "T28C6.6"

col-3 encodes a collagen protein that affects body morphogenesis, larval viability, and locomotion in large scale RNAi screens; mRNA is expressed during all developmental stages examined (in embryos, during the L2 to dauer molt, during the dauer to L4 larval molt, and during the L4 to adult molt).

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 88
Specificity index: 0.023

External "T28C6.6" Links

Gene Inhibited

F23H12.4 (sqt-3)

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 121
Relative score: 0.115 (Best raw score= for Gene )
Specificity index: 0.032

External "F23H12.4" Links

Gene Inhibited

T21B4.2 (col-85)

Description of "T21B4.2"

Associated GO Term : structural constituent of cuticle

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 115
Relative score: 0.11 (Best raw score= for Gene )
Specificity index: 0.031

External "T21B4.2" Links

Gene Inhibited

F38A3.2 (ram-2)

Description of "F38A3.2"

ram-2 encodes a cuticle collagen that interacts with unc-6 to affect ray cell migration, and interacts with unc-5 and unc-6 to affect embryonic viability; also affects ray morphology in males such that the structural cells and the hypodermis of the rays are swollen in mutants.

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 393
Relative score: 0.375 (Best raw score= for Gene )
Specificity index: 0.104

External "F38A3.2" Links

Gene Inhibited

T15B7.4 (col-142)

Description of "T15B7.4"

Associated GO Term : structural constituent of cuticle

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window	Raw score: 216 Relative score: 0.206 (Best raw score= for Gene ) Specificity index: 0.057
Wormbase (BLAST)	RNAi primary

External "T15B7.4" Links

Gene Inhibited

K04H4.1 (emb-9)

Description of "K04H4.1"

emb-9 encodes the alpha-1 chain of Type IV basement membrane collagen most closely equivalent to human COL4A1 (OMIM:120130) on the basis of biological function; EMB-9 forms heterotrimeric Type IV collagen with LET-2, the alpha-2-like chain, and is required for the assembly and/or secretion of LET-2; EMB-9 is essential for embryonic morphogenesis, particularly epidermal elongation, and for larval development; EMB-9 is expresed primarily by body wall muscles and some somatic cells of the gonad and is detected in nearly all basement membranes.

Evidence for Inhibition

Sliding Window

Raw score: 1820
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.278

External "K04H4.1" Links

Gene Inhibited

C29F4.1 (col-125)

Description of "C29F4.1"

Associated GO Term : structural constituent of cuticle

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window