Ace View of JA:T20F5.2 | |||
Gene Inhibited | T20F5.2 (pbs-4) | ||
Description of "T20F5.2" | pbs-4 encodes a B-type subunit of the 26S proteasome's 20S protease core particle; by homology, PBS-4 is predicted to function in ATP/ubiquitin-dependent nonlysosomal protein degradation; loss of pbs-4 activity via RNAi indicates that, in C. elegans, PBS-4 is required for embryonic, germline, and larval development. | ||
KOG Annotation  | 20S proteasome, regulatory subunit beta type PSMB2/PRE1 |
||
Evidence for Inhibition | |||
External "T20F5.2" Links | |||
Embryonic | Emb Penetrance 100 % | ||
Phenotype | Ocs
1-12 cell arrest |
||
Movies/Stacks/Images | |||
Laboratory | JA | ||
RNAi Reagent & Type | sjj_T20F5.2 (PCR_reagent) | ||
Reference | Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...." | ||
Date | 2000-11-16 | ||
Gene Plot of T20F5.2 | |||