RNAi Experiment: JA:T22C8.8 |
Ace View of JA:T22C8.8
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Genes Inhibited |
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Gene Inhibited |
T22C8.8 (vab-9) |
Description of "T22C8.8" |
vab-9 encodes a claudin homolog orthologous to human brain cell membrane protein 1 (BCMP1) and Drosophila CG6982; VAB-9 colocalizes with HMP-1 to an apical layer of the adherens junctions of all epithelial cells, one layer more apically than AJM-1; vab-9 mutants have disorganized F-actin at the adherens junction, implying that VAB-9 links junctions to circumferential actin filaments; VAB-9 is also expressed in the nerve ring; VAB-9 requires the cadherin HMR-1 to localize to the cell membrane, and both alpha-catenin (HMP-1) and beta-catenin (HMP-2) to remain at the cell junction after membrane localization. |
KOG Annotation  |
Brain cell membrane protein 1 (BCMP1)
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (II:8636316..8637997)
Transcript overlap: 770 nt |
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Sliding Window |
Raw score: 686
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "T22C8.8" Links |
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JA:T22C8.8 Phenotypes |
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Phenotype |
WT
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JA:T22C8.8 Experiment Details |
Ace View |
Laboratory |
JA |
RNAi Reagent & Type |
sjj_T22C8.8 (PCR_reagent) |
Reference |
Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." |
Date |
2003-1-10 |
Gene Plot of T22C8.8 |
Browse using GBrowse
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