Ace View of JA:T28F12.2a | |||
Gene Inhibited | T28F12.2 (unc-62) | ||
Description of "T28F12.2" | unc-62 encodes a Meis-class homeodomain protein required for posterior embryonic morphogenesis, male tail morphogenesis, commissure formation by VD and DD motor neurons, vulval morphogenesis, and normal locomotion; UNC-62 is orthologous to Drosophila HOMOTHORAX; both maternal-effect unc-62 alleles and the zygotic lethal unc-62(s472) allele phenotypically resemble mutations of the caudal ortholog pal-1; RNAi of the Pbc-class ceh-20 and ceh-40 homeodomain genes strongly enhances the hypomorphic unc-62(e644) allele to give either a strong loss-of-function or null-like phenotype, while overexpression of ceh-20 enhances the lethality of some unc-62 alleles. | ||
Evidence for Inhibition | |||
External "T28F12.2" Links | |||
Embryonic | Emb Penetrance 80 % | ||
Adult | Dpy Egl Unc |
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Laboratory | JA | ||
RNAi Reagent & Type | sjj_T28F12.2a (PCR_reagent) | ||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | ||
Date | 2003-1-10 | ||
Gene Plot of T28F12.2 | |||