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RNAi Experiment: JA:VF36H2L.1 Ace View of JA:VF36H2L.1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  VF36H2L.1 (aph-1)
Description of "VF36H2L.1"  aph-1 encodes an unfamiliar protein predicted to have seven transmembrane domains; APH-1 is a component of the GLP-1/LIN-12 (Notch) pathway, is required maternally for embryonic viability, and also affects morphogenesis, egg laying, germ line proliferation, and translocation of APH-2 to the cell surface; with PEN-2, APH-1 is required for Notch pathway signaling, gamma-secretase cleavage of beta-amyloid precursor protein, and presenilin protein accumulation.
KOG Annotation  Predicted membrane protein
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:9232266..9233354)
Transcript overlap: 748 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 685
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "VF36H2L.1" Links  Wormbase NCBI
JA:VF36H2L.1 Phenotypes Help with Phenotypes
Adult  Unc
JA:VF36H2L.1 Experiment Details Ace View
Laboratory  JA
RNAi Reagent & Type  sjj_VF36H2L.1 (PCR_reagent)
Reference  Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...."
Date  2000-11-16
Gene Plot of VF36H2L.1 Browse using GBrowse
Gene Graph