Ace View of JA:W02G9.1 | ||||
Gene Inhibited | W02G9.1 (ndx-2) | |||
Description of "W02G9.1" | ndx-2 encodes a NUDIX hydrolase; by sequence comparison, NDX-2 is predicted to be orthologous to human NUDT5 which, in vitro, possesses ADP-sugar diphosphatase activity; in C. elegans, loss of ndx-2 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, consistent with the proposed nonessential roles for Nudix proteins in eliminating potentially toxic nucleotide metabolites from cells and modulating levels of metabolic intermediates by shuttling them into alternative biochemical pathways. | |||
KOG Annotation  | Nucleoside diphosphate-sugar hydrolase of the MutT (NUDIX) family |
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Evidence for Inhibition | ||||
External "W02G9.1" Links | ||||
Gene Inhibited | F36F12.4 | |||
KOG Annotation  | Extracellular protein with conserved cysteines |
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Evidence for Inhibition |
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External "F36F12.4" Links | ||||
Phenotype | WT |
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Laboratory | JA | |||
RNAi Reagent & Type | sjj_W02G9.1 (PCR_reagent) | |||
Reference | Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." | |||
Date | 2003-1-10 | |||
Gene Plot of W02G9.1 | ||||
Gene Plot of F36F12.4 | ||||