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RNAi Experiment: JA:W03D8.6 Ace View of JA:W03D8.6
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  W03D8.6 (itx-1)
Description of "W03D8.6"  itx-1 encodes one of two Caspr orthologues found in the C. elegans genome; Caspr proteins belong to the Neurexin superfamily and are involved in mediating cell-cell contacts and in the formation of specialized membrane-domains in polarized epithelial and nerve cells; RNA interference of itx-1 suggests that itx-1 is involved in the correct positioning and maintenance of apical junctions and in maintaining epithelial integrity in the gut; gfp-reporter studies indicate that ITX-1 is expressed in intestinal cell epithelia and in the socket cells of the inner and outer labial sensilla; immunofluorescence studies indicate that ITX-1 localizes to the baso-lateral membranes of intestinal epithelia.
KOG Annotation  Neurexin IV
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:2811142..2812282)
Transcript overlap: 904 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 822
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "W03D8.6" Links  Wormbase NCBI
JA:W03D8.6 Phenotypes Help with Phenotypes
Phenotype  WT
JA:W03D8.6 Experiment Details Ace View
Laboratory  JA
RNAi Reagent & Type  sjj_W03D8.6 (PCR_reagent)
Reference  Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...."
Date  2000-11-16
Gene Plot of W03D8.6 Browse using GBrowse
Gene Graph