Link to Y105E8A.6RNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
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RNAi Experiment: JA:Y105E8C.s Ace View of JA:Y105E8C.s
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y105E8A.6 (unc-95)
Description of "Y105E8A.6"  unc-95 encodes a LIM domain-containing protein related to Drosophila and vertebrate paxillins; UNC-95 is required for locomotion and organization of thick and thin filaments in body wall muscle; by homology, UNC-95 may function as an anchor protein that links signaling and cytoskeletal proteins at focal adhesions; in vitro, UNC-95 interacts with RNF-5, a RING finger protein that may function as an E3 ligase to regulate UNC-95 levels via ubiquitin-mediated degradation; UNC-95 is expressed in body-wall and vulval muscles, and co-localizes with RNF-5 to muscle dense bodies (focal adhesion-like attachment sites).
KOG Annotation  Adaptor protein Enigma and related PDZ-LIM proteins
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:14381171..14383028)
Transcript overlap: 905 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 821
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y105E8A.6" Links  Wormbase NCBI
JA:Y105E8C.s Phenotypes Help with Phenotypes
Phenotype  WT
JA:Y105E8C.s Experiment Details Ace View
Laboratory  JA
RNAi Reagent & Type  sjj_Y105E8C.s (PCR_reagent)
Reference  Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...."
Date  2000-11-16
Gene Plot of Y105E8A.6 Browse using GBrowse
Gene Graph