RNAi Experiment: JA:Y105E8C.s |
Ace View of JA:Y105E8C.s
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Genes Inhibited |
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Gene Inhibited |
Y105E8A.6 (unc-95) |
Description of "Y105E8A.6" |
unc-95 encodes a LIM domain-containing protein related to Drosophila and vertebrate paxillins; UNC-95 is required for locomotion and organization of thick and thin filaments in body wall muscle; by homology, UNC-95 may function as an anchor protein that links signaling and cytoskeletal proteins at focal adhesions; in vitro, UNC-95 interacts with RNF-5, a RING finger protein that may function as an E3 ligase to regulate UNC-95 levels via ubiquitin-mediated degradation; UNC-95 is expressed in body-wall and vulval muscles, and co-localizes with RNF-5 to muscle dense bodies (focal adhesion-like attachment sites). |
KOG Annotation  |
Adaptor protein Enigma and related PDZ-LIM proteins
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (I:14381171..14383028)
Transcript overlap: 905 nt |
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Sliding Window |
Raw score: 821
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "Y105E8A.6" Links |
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JA:Y105E8C.s Phenotypes |
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Phenotype |
WT
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JA:Y105E8C.s Experiment Details |
Ace View |
Laboratory |
JA |
RNAi Reagent & Type |
sjj_Y105E8C.s (PCR_reagent) |
Reference |
Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...." |
Date |
2000-11-16 |
Gene Plot of Y105E8A.6 |
Browse using GBrowse
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