RNAi Experiment: JA:Y43F4B.6 |
Ace View of JA:Y43F4B.6
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Genes Inhibited |
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Gene Inhibited |
Y43F4B.6 (klp-19) |
Description of "Y43F4B.6" |
klp-19 encodes a plus-end-directed microtubule motor protein that is most closely related to motors of the kinesin-4 family; KLP-19 activity is essential for embryonic and larval development and is required for generating a force that aligns sister chromatid kinetochores directly opposite the spindle poles thus ensuring proper holocentric chromosome segregation; KLP-19 expression is detected in embryos and in the gonad, where it is most strongly expressed in distal mitotic nuclei and in late meiotic prophase nucleoplasm; during meiosis and mitosis, KLP-19 expression is dynamic and is detected in the nucleoplasm, the spindle body, in association with condensed chromosomes (particularly between homologous chromosomes), and in the spindle interzone. |
KOG Annotation  |
Kinesin-like protein
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (III:13305692..13306839)
Transcript overlap: 1031 nt |
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Sliding Window |
Raw score: 989
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "Y43F4B.6" Links |
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JA:Y43F4B.6 Phenotypes |
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Embryonic |
Emb Penetrance 100 % |
JA:Y43F4B.6 Experiment Details |
Ace View |
Laboratory |
JA |
RNAi Reagent & Type |
sjj_Y43F4B.6 (PCR_reagent) |
Reference |
Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." |
Date |
2003-1-10 |
Gene Plot of Y43F4B.6 |
Browse using GBrowse
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