RNAi Experiment: JA:Y46H3A.d |
Ace View of JA:Y46H3A.d
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Genes Inhibited |
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Gene Inhibited |
Y46H3A.3 (hsp-16.2) |
Description of "Y46H3A.3" |
hsp-16.2 encodes a 16-kD heat shock protein (HSP) that is a member of the hsp16/hsp20/alphaB-crystallin (HSP16) family of heat shock proteins; hsp-16.2 expression, strongest in intestine and pharynx, is induced in response to heat shock or other environmental stresses; HSP-16.2 has been shown to interact with intracellular human beta amyloid peptide, a primary component of the extracellular plaques found in Alzheimer's disease; HSP-16.2 is likely to function as a passive ligand temporarily preventing unfolded proteins from aggregating. |
KOG Annotation  |
Alpha crystallins
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (V:1803987..1804819)
Transcript overlap: 545 nt |
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Sliding Window |
Raw score: 482
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "Y46H3A.3" Links |
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JA:Y46H3A.d Phenotypes |
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Phenotype |
WT
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JA:Y46H3A.d Experiment Details |
Ace View |
Laboratory |
JA |
RNAi Reagent & Type |
sjj_Y46H3A.d (PCR_reagent) |
Reference |
Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." |
Date |
2003-1-10 |
Gene Plot of Y46H3A.3 |
Browse using GBrowse
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