RNAi Experiment: JA:Y48B6A.4 |
Ace View of JA:Y48B6A.4
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Genes Inhibited |
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Gene Inhibited |
Y48B6A.4 (eat-2) |
Description of "Y48B6A.4" |
eat-2 encodes a beta subunit of the nicotinic acetylcholine receptor (nAChR) superfamily which encode ligand-gated ion channels that regulate fast action of acetylcholine at neuromuscular junctions and in the nervous system; EAT-2 regulates the rate of pharyngeal pumping by by affecting MC pharyngeal neuron transmission, and is required for neurotransmission from the MC pharyngeal neuron to pharyngeal muscle, in which it is expressed, and also affects life span and defecation; eat-2 genetically interacts with eat-18, which encodes a predicted transcriptional activator also expressed in pharyngeal muscle. |
KOG Annotation  |
Acetylcholine receptor
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (II:14168636..14171390)
Transcript overlap: 1015 nt |
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Sliding Window |
Raw score: 931
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "Y48B6A.4" Links |
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JA:Y48B6A.4 Phenotypes |
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Phenotype |
WT
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JA:Y48B6A.4 Experiment Details |
Ace View |
Laboratory |
JA |
RNAi Reagent & Type |
sjj_Y48B6A.4 (PCR_reagent) |
Reference |
Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." |
Date |
2003-1-10 |
Gene Plot of Y48B6A.4 |
Browse using GBrowse
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