RNAi Experiment: JA:Y48G1A_54.b |
Ace View of JA:Y48G1A_54.b
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Genes Inhibited |
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Gene Inhibited |
Y48G1A.5 (imb-5) |
Description of "Y48G1A.5" |
imb-5 encodes an importin-beta-like protein orthologous to mammalian CAS proteins (cellular apoptosis susceptibility) and Saccharomyces cerevisiae CSE1 (chromosome segregation 1); IMB-5 is predicted to function in nuclear transport of proteins required for mitotic progression or apoptosis as well as in re-export of importin-alpha, a nuclear import protein; in C. elegans, IMB-5 is essential for embryogenesis and required for normal pronuclear envelope dynamics, and may also play a role in vulval morphogenesis. |
KOG Annotation  |
Nuclear export receptor CSE1/CAS (importin beta superfamily)
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (I:319957..322435)
Transcript overlap: 1776 nt |
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Sliding Window |
Raw score: 1713
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "Y48G1A.5" Links |
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JA:Y48G1A_54.b Phenotypes |
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Embryonic |
Emb Penetrance 100 % |
Phenotype |
Pna
<200 cells
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Movies/Stacks/Images |
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JA:Y48G1A_54.b Experiment Details |
Ace View |
Laboratory |
JA |
RNAi Reagent & Type |
sjj_Y48G1A_54.b (PCR_reagent) |
Remark |
P1 division late |
Reference |
Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...." |
Date |
2000-11-16 |
Gene Plot of Y48G1A.5 |
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