RNAi Card Page

RNAi Experiment: JA:Y4C6A.c

Ace View of JA:Y4C6A.c

Genes Inhibited

Gene Inhibited

Y59E9AR.7

Description of "Y59E9AR.7"

Associated GO Term : structural molecule activity

Evidence for Inhibition

Sliding Window	Raw score: 186 Specificity index: 0.045
Wormbase (BLAST)	RNAi secondary

External "Y59E9AR.7" Links

Gene Inhibited

R05F9.3 (msp-32)

Description of "R05F9.3"

msp-32 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-32 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the msp family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 74 Relative score: 0.222 (Best raw score= for Gene ) Specificity index: 0.018
Wormbase (BLAST)	RNAi secondary

External "R05F9.3" Links

Gene Inhibited

K07F5.2 (msp-10)

Description of "K07F5.2"

msp-10 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 81 Specificity index: 0.02
Wormbase (BLAST)	RNAi secondary

External "K07F5.2" Links

Gene Inhibited

C09B9.6 (msp-55)

Description of "C09B9.6"

msp-55 encodes a member of the major sperm protein family.

Evidence for Inhibition

Sliding Window	Raw score: 188 Relative score: 0.563 (Best raw score= for Gene ) Specificity index: 0.045
Wormbase (BLAST)	RNAi primary

External "C09B9.6" Links

Gene Inhibited

F36H12.7 (msp-19)

Description of "F36H12.7"

msp-19 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-19 has a homolog in C. briggsae as predicted by the Wobble Aware Bulk Aligner (WABA); the msp gene family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 217 Relative score: 0.65 (Best raw score= for Gene ) Specificity index: 0.052
Wormbase (BLAST)	RNAi primary

External "F36H12.7" Links

Gene Inhibited

Y59E9AR.1

Description of "Y59E9AR.1"

Associated GO Term : structural molecule activity

Evidence for Inhibition

Sliding Window	Raw score: 186 Relative score: 0.557 (Best raw score= for Gene ) Specificity index: 0.045
Wormbase (BLAST)	RNAi secondary

External "Y59E9AR.1" Links

Gene Inhibited

R13H9.2 (msp-57)

Description of "R13H9.2"

msp-57 encodes a member of the major sperm protein family.

Evidence for Inhibition

Sliding Window	Raw score: 180 Relative score: 0.539 (Best raw score= for Gene ) Specificity index: 0.043
Wormbase (BLAST)	RNAi primary

External "R13H9.2" Links

Gene Inhibited

K08F4.8 (msp-38)

Description of "K08F4.8"

msp-38 encodes a member of the major sperm protein family; msp-38 has a C. briggsae homolog as predicted by the Wobble Bulk Aware Bulk Aligner (WABA).

Evidence for Inhibition

Sliding Window	Raw score: 108 Relative score: 0.323 (Best raw score= for Gene ) Specificity index: 0.026
Wormbase (BLAST)	RNAi secondary

External "K08F4.8" Links

Gene Inhibited

ZK546.3

Description of "ZK546.3"

Associated GO Term : structural molecule activity

Evidence for Inhibition

Sliding Window	Raw score: 67 Specificity index: 0.016
Wormbase (BLAST)	RNAi secondary

External "ZK546.3" Links

Gene Inhibited

ZK354.5 (msp-51)

Description of "ZK354.5"

msp-51 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-51 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 238 Relative score: 0.713 (Best raw score= for Gene ) Specificity index: 0.058
Wormbase (BLAST)	RNAi primary

External "ZK354.5" Links

Gene Inhibited

ZK354.10 (msp-58)

Description of "ZK354.10"

msp-58 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 253 Relative score: 0.757 (Best raw score= for Gene ) Specificity index: 0.061
Wormbase (BLAST)	RNAi primary

External "ZK354.10" Links

Gene Inhibited

T13F2.10 (msp-79)

Description of "T13F2.10"

msp-79 encodes a member of the major sperm protein family.

Evidence for Inhibition

Sliding Window	Raw score: 81 Specificity index: 0.02
Wormbase (BLAST)	RNAi secondary

External "T13F2.10" Links

Gene Inhibited

F32B6.6 (msp-77)

Description of "F32B6.6"

msp-77 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 79 Relative score: 0.237 (Best raw score= for Gene ) Specificity index: 0.019
Wormbase (BLAST)	RNAi secondary

External "F32B6.6" Links

Gene Inhibited

F58A6.8 (msp-45)

Description of "F58A6.8"

msp-45 encodes a member of the major sperm protein family.

Evidence for Inhibition

Sliding Window	Raw score: 106 Relative score: 0.317 (Best raw score= for Gene ) Specificity index: 0.026
Wormbase (BLAST)	RNAi secondary

External "F58A6.8" Links

Gene Inhibited

R13H9.4 (msp-53)

Description of "R13H9.4"

msp-53 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-53 has a C. briggsae homolog as identified by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 187 Relative score: 0.56 (Best raw score= for Gene ) Specificity index: 0.045
Wormbase (BLAST)	RNAi primary

External "R13H9.4" Links

Gene Inhibited

ZK354.4 (msp-113)

Description of "ZK354.4"

msp-113 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-113 has a C. briggsae homolog as detected by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; the msp-113 promoter region contains two conserved cis elements that are recognition sites for elt-1, a gene that encodes a homolog of the vertebrate GATA transcription factor family; this suggests that a MSP protein is a potential target for ELT-1 in the germ-line; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 334 Relative score: 1 (This gene has the best score for this RNAi reagent) Specificity index: 0.081
Wormbase (BLAST)	RNAi primary

External "ZK354.4" Links

Gene Inhibited

R05F9.8 (msp-33)

Description of "R05F9.8"

msp-33 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-33 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 103 Relative score: 0.308 (Best raw score= for Gene ) Specificity index: 0.025
Wormbase (BLAST)	RNAi secondary

External "R05F9.8" Links

Gene Inhibited

ZK354.11 (msp-59)

Description of "ZK354.11"

msp-59 encodes a member of the major sperm protein family.

Evidence for Inhibition

Sliding Window	Raw score: 200 Relative score: 0.599 (Best raw score= for Gene ) Specificity index: 0.048
Wormbase (BLAST)	RNAi primary

External "ZK354.11" Links

Gene Inhibited

T13F2.11 (msp-78)

Description of "T13F2.11"

msp-78 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 62 Relative score: 0.186 (Best raw score= for Gene ) Specificity index: 0.015
Wormbase (BLAST)	RNAi secondary

External "T13F2.11" Links

Gene Inhibited

C34F11.6 (msp-49)

Description of "C34F11.6"

msp-49 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 76 Relative score: 0.228 (Best raw score= for Gene ) Specificity index: 0.018
Wormbase (BLAST)	RNAi secondary

External "C34F11.6" Links

Gene Inhibited

F26G1.7 (msp-3)

Description of "F26G1.7"

msp-3 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-3 is similar in nucleotide sequence to the msp genes from the nematode Onchocerca volvulus; the msp gene family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP proteins assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 67 Relative score: 0.201 (Best raw score= for Gene ) Specificity index: 0.016
Wormbase (BLAST)	RNAi secondary

External "F26G1.7" Links

Gene Inhibited

C04G2.4 (msp-36)

Description of "C04G2.4"

msp-36 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family comprises of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSP is involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP assembles into fibrous networks that drives movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 91 Relative score: 0.272 (Best raw score= for Gene ) Specificity index: 0.022
Wormbase (BLAST)	RNAi secondary

External "C04G2.4" Links

Gene Inhibited

ZK354.1 (msp-65)

Description of "ZK354.1"

msp-65 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 285 Relative score: 0.853 (Best raw score= for Gene ) Specificity index: 0.069
Wormbase (BLAST)	RNAi primary

External "ZK354.1" Links

Gene Inhibited

F58A6.9

Description of "F58A6.9"

Associated GO Term : structural molecule activity

Evidence for Inhibition

Sliding Window	Raw score: 83 Relative score: 0.249 (Best raw score= for Gene ) Specificity index: 0.02
Wormbase (BLAST)	RNAi secondary

External "F58A6.9" Links

Gene Inhibited

Y59H11AM.1

Description of "Y59H11AM.1"

Associated GO Term : structural molecule activity

Evidence for Inhibition

Sliding Window	Raw score: 154 Relative score: 0.461 (Best raw score= for Gene ) Specificity index: 0.037
Wormbase (BLAST)	RNAi secondary

External "Y59H11AM.1" Links

Gene Inhibited

K07F5.3 (msp-56)

Description of "K07F5.3"

msp-56 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 81 Relative score: 0.243 (Best raw score= for Gene ) Specificity index: 0.02
Wormbase (BLAST)	RNAi secondary

External "K07F5.3" Links

Gene Inhibited

F36H12.6 (msp-52)

Description of "F36H12.6"

msp-52 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition

Sliding Window	Raw score: 142 Relative score: 0.425 (Best raw score= for Gene ) Specificity index: 0.034
Wormbase (BLAST)	RNAi primary

External "F36H12.6" Links

Gene Inhibited

R05F9.13 (msp-31)

Description of "R05F9.13"

msp-31 encodes a member of the major sperm protein family; msp-31 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); expression is enriched in sperm.

Evidence for Inhibition

Sliding Window	Raw score: 127 Relative score: 0.38 (Best raw score= for Gene ) Specificity index: 0.031
Wormbase (BLAST)	RNAi secondary

External "R05F9.13" Links

Gene Inhibited

F59A6.8 (msp-71)

Description of "F59A6.8"

msp-71 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.

Evidence for Inhibition