RNAi Experiment: JA:Y4C6A.c |
Ace View of JA:Y4C6A.c
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Genes Inhibited |
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Gene Inhibited |
Y59E9AR.7 |
Description of "Y59E9AR.7" |
Associated GO Term : structural molecule activity |
Evidence for Inhibition |
Sliding Window |
Raw score: 186
Specificity index: 0.045 |
Wormbase (BLAST) |
RNAi secondary |
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External "Y59E9AR.7" Links |
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Gene Inhibited |
R05F9.3 (msp-32) |
Description of "R05F9.3" |
msp-32 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-32 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the msp family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 74
Relative score: 0.222 (Best raw score= for Gene )
Specificity index: 0.018 |
Wormbase (BLAST) |
RNAi secondary |
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External "R05F9.3" Links |
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Gene Inhibited |
K07F5.2 (msp-10) |
Description of "K07F5.2" |
msp-10 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 81
Specificity index: 0.02 |
Wormbase (BLAST) |
RNAi secondary |
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External "K07F5.2" Links |
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Gene Inhibited |
C09B9.6 (msp-55) |
Description of "C09B9.6" |
msp-55 encodes a member of the major sperm protein family. |
Evidence for Inhibition |
Sliding Window |
Raw score: 188
Relative score: 0.563 (Best raw score= for Gene )
Specificity index: 0.045 |
Wormbase (BLAST) |
RNAi primary |
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External "C09B9.6" Links |
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Gene Inhibited |
F36H12.7 (msp-19) |
Description of "F36H12.7" |
msp-19 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-19 has a homolog in C. briggsae as predicted by the Wobble Aware Bulk Aligner (WABA); the msp gene family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 217
Relative score: 0.65 (Best raw score= for Gene )
Specificity index: 0.052 |
Wormbase (BLAST) |
RNAi primary |
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External "F36H12.7" Links |
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Gene Inhibited |
Y59E9AR.1 |
Description of "Y59E9AR.1" |
Associated GO Term : structural molecule activity |
Evidence for Inhibition |
Sliding Window |
Raw score: 186
Relative score: 0.557 (Best raw score= for Gene )
Specificity index: 0.045 |
Wormbase (BLAST) |
RNAi secondary |
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External "Y59E9AR.1" Links |
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Gene Inhibited |
R13H9.2 (msp-57) |
Description of "R13H9.2" |
msp-57 encodes a member of the major sperm protein family. |
Evidence for Inhibition |
Sliding Window |
Raw score: 180
Relative score: 0.539 (Best raw score= for Gene )
Specificity index: 0.043 |
Wormbase (BLAST) |
RNAi primary |
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External "R13H9.2" Links |
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Gene Inhibited |
K08F4.8 (msp-38) |
Description of "K08F4.8" |
msp-38 encodes a member of the major sperm protein family; msp-38 has a C. briggsae homolog as predicted by the Wobble Bulk Aware Bulk Aligner (WABA). |
Evidence for Inhibition |
Sliding Window |
Raw score: 108
Relative score: 0.323 (Best raw score= for Gene )
Specificity index: 0.026 |
Wormbase (BLAST) |
RNAi secondary |
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External "K08F4.8" Links |
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Gene Inhibited |
ZK546.3 |
Description of "ZK546.3" |
Associated GO Term : structural molecule activity |
Evidence for Inhibition |
Sliding Window |
Raw score: 67
Specificity index: 0.016 |
Wormbase (BLAST) |
RNAi secondary |
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External "ZK546.3" Links |
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Gene Inhibited |
ZK354.5 (msp-51) |
Description of "ZK354.5" |
msp-51 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-51 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 238
Relative score: 0.713 (Best raw score= for Gene )
Specificity index: 0.058 |
Wormbase (BLAST) |
RNAi primary |
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External "ZK354.5" Links |
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Gene Inhibited |
ZK354.10 (msp-58) |
Description of "ZK354.10" |
msp-58 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 253
Relative score: 0.757 (Best raw score= for Gene )
Specificity index: 0.061 |
Wormbase (BLAST) |
RNAi primary |
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External "ZK354.10" Links |
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Gene Inhibited |
T13F2.10 (msp-79) |
Description of "T13F2.10" |
msp-79 encodes a member of the major sperm protein family. |
Evidence for Inhibition |
Sliding Window |
Raw score: 81
Specificity index: 0.02 |
Wormbase (BLAST) |
RNAi secondary |
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External "T13F2.10" Links |
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Gene Inhibited |
F32B6.6 (msp-77) |
Description of "F32B6.6" |
msp-77 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 79
Relative score: 0.237 (Best raw score= for Gene )
Specificity index: 0.019 |
Wormbase (BLAST) |
RNAi secondary |
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External "F32B6.6" Links |
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Gene Inhibited |
F58A6.8 (msp-45) |
Description of "F58A6.8" |
msp-45 encodes a member of the major sperm protein family. |
Evidence for Inhibition |
Sliding Window |
Raw score: 106
Relative score: 0.317 (Best raw score= for Gene )
Specificity index: 0.026 |
Wormbase (BLAST) |
RNAi secondary |
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External "F58A6.8" Links |
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Gene Inhibited |
R13H9.4 (msp-53) |
Description of "R13H9.4" |
msp-53 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-53 has a C. briggsae homolog as identified by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 187
Relative score: 0.56 (Best raw score= for Gene )
Specificity index: 0.045 |
Wormbase (BLAST) |
RNAi primary |
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External "R13H9.4" Links |
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Gene Inhibited |
ZK354.4 (msp-113) |
Description of "ZK354.4" |
msp-113 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-113 has a C. briggsae homolog as detected by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; the msp-113 promoter region contains two conserved cis elements that are recognition sites for elt-1, a gene that encodes a homolog of the vertebrate GATA transcription factor family; this suggests that a MSP protein is a potential target for ELT-1 in the germ-line; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 334
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.081 |
Wormbase (BLAST) |
RNAi primary |
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External "ZK354.4" Links |
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Gene Inhibited |
R05F9.8 (msp-33) |
Description of "R05F9.8" |
msp-33 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-33 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 103
Relative score: 0.308 (Best raw score= for Gene )
Specificity index: 0.025 |
Wormbase (BLAST) |
RNAi secondary |
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External "R05F9.8" Links |
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Gene Inhibited |
ZK354.11 (msp-59) |
Description of "ZK354.11" |
msp-59 encodes a member of the major sperm protein family. |
Evidence for Inhibition |
Sliding Window |
Raw score: 200
Relative score: 0.599 (Best raw score= for Gene )
Specificity index: 0.048 |
Wormbase (BLAST) |
RNAi primary |
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External "ZK354.11" Links |
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Gene Inhibited |
T13F2.11 (msp-78) |
Description of "T13F2.11" |
msp-78 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 62
Relative score: 0.186 (Best raw score= for Gene )
Specificity index: 0.015 |
Wormbase (BLAST) |
RNAi secondary |
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External "T13F2.11" Links |
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Gene Inhibited |
C34F11.6 (msp-49) |
Description of "C34F11.6" |
msp-49 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 76
Relative score: 0.228 (Best raw score= for Gene )
Specificity index: 0.018 |
Wormbase (BLAST) |
RNAi secondary |
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External "C34F11.6" Links |
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Gene Inhibited |
F26G1.7 (msp-3) |
Description of "F26G1.7" |
msp-3 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-3 is similar in nucleotide sequence to the msp genes from the nematode Onchocerca volvulus; the msp gene family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP proteins assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 67
Relative score: 0.201 (Best raw score= for Gene )
Specificity index: 0.016 |
Wormbase (BLAST) |
RNAi secondary |
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External "F26G1.7" Links |
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Gene Inhibited |
C04G2.4 (msp-36) |
Description of "C04G2.4" |
msp-36 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family comprises of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSP is involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP assembles into fibrous networks that drives movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 91
Relative score: 0.272 (Best raw score= for Gene )
Specificity index: 0.022 |
Wormbase (BLAST) |
RNAi secondary |
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External "C04G2.4" Links |
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Gene Inhibited |
ZK354.1 (msp-65) |
Description of "ZK354.1" |
msp-65 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 285
Relative score: 0.853 (Best raw score= for Gene )
Specificity index: 0.069 |
Wormbase (BLAST) |
RNAi primary |
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External "ZK354.1" Links |
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Gene Inhibited |
F58A6.9 |
Description of "F58A6.9" |
Associated GO Term : structural molecule activity |
Evidence for Inhibition |
Sliding Window |
Raw score: 83
Relative score: 0.249 (Best raw score= for Gene )
Specificity index: 0.02 |
Wormbase (BLAST) |
RNAi secondary |
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External "F58A6.9" Links |
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Gene Inhibited |
Y59H11AM.1 |
Description of "Y59H11AM.1" |
Associated GO Term : structural molecule activity |
Evidence for Inhibition |
Sliding Window |
Raw score: 154
Relative score: 0.461 (Best raw score= for Gene )
Specificity index: 0.037 |
Wormbase (BLAST) |
RNAi secondary |
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External "Y59H11AM.1" Links |
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Gene Inhibited |
K07F5.3 (msp-56) |
Description of "K07F5.3" |
msp-56 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 81
Relative score: 0.243 (Best raw score= for Gene )
Specificity index: 0.02 |
Wormbase (BLAST) |
RNAi secondary |
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External "K07F5.3" Links |
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Gene Inhibited |
F36H12.6 (msp-52) |
Description of "F36H12.6" |
msp-52 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 142
Relative score: 0.425 (Best raw score= for Gene )
Specificity index: 0.034 |
Wormbase (BLAST) |
RNAi primary |
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External "F36H12.6" Links |
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Gene Inhibited |
R05F9.13 (msp-31) |
Description of "R05F9.13" |
msp-31 encodes a member of the major sperm protein family; msp-31 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); expression is enriched in sperm. |
Evidence for Inhibition |
Sliding Window |
Raw score: 127
Relative score: 0.38 (Best raw score= for Gene )
Specificity index: 0.031 |
Wormbase (BLAST) |
RNAi secondary |
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External "R05F9.13" Links |
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Gene Inhibited |
F59A6.8 (msp-71) |
Description of "F59A6.8" |
msp-71 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 102
Relative score: 0.305 (Best raw score= for Gene )
Specificity index: 0.025 |
Wormbase (BLAST) |
RNAi secondary |
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External "F59A6.8" Links |
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JA:Y4C6A.c Phenotypes |
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Phenotype |
WT
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JA:Y4C6A.c Experiment Details |
Ace View |
Laboratory |
JA |
RNAi Reagent & Type |
sjj_Y4C6A.c (PCR_reagent) |
Reference |
Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." |
Date |
2003-1-10 |
Gene Plot of Y59E9AR.7 |
Browse using GBrowse
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Gene Plot of R05F9.3 |
Browse using GBrowse
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Gene Plot of K07F5.2 |
Browse using GBrowse
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Gene Plot of C09B9.6 |
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Gene Plot of ZK546.3 |
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Gene Plot of F36H12.7 |
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Gene Plot of Y59E9AR.1 |
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Gene Plot of R13H9.2 |
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Gene Plot of K08F4.8 |
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Gene Plot of F58A6.8 |
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Gene Plot of F32B6.6 |
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Gene Plot of T13F2.10 |
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Gene Plot of ZK354.10 |
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Gene Plot of ZK354.5 |
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Gene Plot of R05F9.8 |
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Gene Plot of ZK354.4 |
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Gene Plot of R13H9.4 |
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Gene Plot of C34F11.6 |
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Gene Plot of T13F2.11 |
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Gene Plot of ZK354.11 |
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Gene Plot of F26G1.7 |
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Gene Plot of C04G2.4 |
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Gene Plot of F58A6.9 |
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Gene Plot of ZK354.1 |
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Gene Plot of Y59H11AM.1 |
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Gene Plot of K07F5.3 |
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Gene Plot of F36H12.6 |
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Gene Plot of F59A6.8 |
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Gene Plot of R05F9.13 |
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