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RNAi Experiment: JA:Y54E10B_159.b Ace View of JA:Y54E10B_159.b
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y54E10BR.7 (mod-5)
Description of "Y54E10BR.7"  mod-5 encodes a Na[+],Cl[-]-dependent serotonin transporter that is required for serotonin uptake by neurosecretory motor neurons and for the experience-dependent enhanced slowing response to food; MOD-5 has serotonin transport activity in cell culture, and is a target of the serotonin uptake inhibitor fluoxetine (Prozac) in vivo; MOD-5 is orthologous to the human serotonin transporter (SLC6A4, OMIM:182138, associated with varying levels of neuroticism, introversion, and anxiety).
KOG Annotation  Sodium-neurotransmitter symporter
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:3040832..3043316)
Transcript overlap: 889 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 764
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.471
Wormbase (BLAST) RNAi primary
External "Y54E10BR.7" Links  Wormbase NCBI
Gene Inhibited  Y22D7AR.1
Description of "Y22D7AR.1"  Associated GO Term : protein tyrosine phosphatase activity
KOG Annotation  Protein tyrosine phosphatase
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 92
Relative score: 0.12 (Best raw score= for Gene )
Specificity index: 0.057
External "Y22D7AR.1" Links  Wormbase NCBI
Gene Inhibited  E03H4.8
Description of "E03H4.8"  Associated GO Term : protein transporter activity
KOG Annotation  Vesicle coat complex COPI, beta' subunit
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 398
Relative score: 0.521 (Best raw score= for Gene )
Specificity index: 0.246
External "E03H4.8" Links  Wormbase NCBI
Gene Inhibited  T07C12.5 (srj-34)
Evidence for Inhibition 
Sliding Window Raw score: 367
Relative score: 0.48 (Best raw score= for Gene )
Specificity index: 0.226
External "T07C12.5" Links  Wormbase NCBI
JA:Y54E10B_159.b Phenotypes Help with Phenotypes
Phenotype  WT
JA:Y54E10B_159.b Experiment Details Ace View
Laboratory  JA
RNAi Reagent & Type  sjj_Y54E10B_159.b (PCR_reagent)
Reference  Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...."
Date  2000-11-16
Gene Plot of Y54E10BR.7 Browse using GBrowse
Gene Graph
Gene Plot of Y22D7AR.1 Browse using GBrowse
Gene Graph
Gene Plot of E03H4.8 Browse using GBrowse
Gene Graph
Gene Plot of T07C12.5 Browse using GBrowse
Gene Graph