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RNAi Experiment: JA:Y71G12A_187.a Ace View of JA:Y71G12A_187.a
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y71G12B.15 (ubc-3)
Description of "Y71G12B.15"  ubc-3 encodes an E2 ubiquitin-conjugating enzyme orthologous to Saccharomyces cerevisiae and human CDC34 (OMIM:603731) which are involved in regulating protein stability during G1 and G2 cell cycle phase transitions; by homology, UBC-3 is likely required for covalent attachment of ubiquitin to select target proteins to facilitate their degradation; however, as loss of UBC-3 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UBC-3 in C. elegans development and/or behavior is not yet known.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:1699828..1700899)
Transcript overlap: 405 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 342
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y71G12B.15" Links  Wormbase NCBI
JA:Y71G12A_187.a Phenotypes Help with Phenotypes
Phenotype  WT
JA:Y71G12A_187.a Experiment Details Ace View
Laboratory  JA
RNAi Reagent & Type  sjj_Y71G12A_187.a (PCR_reagent)
Reference  Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...."
Date  2000-11-16
Gene Plot of Y71G12B.15 Browse using GBrowse
Gene Graph