RNAi Experiment: JA:Y71G12A_187.a |
Ace View of JA:Y71G12A_187.a
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Genes Inhibited |
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Gene Inhibited |
Y71G12B.15 (ubc-3) |
Description of "Y71G12B.15" |
ubc-3 encodes an E2 ubiquitin-conjugating enzyme orthologous to Saccharomyces cerevisiae and human CDC34 (OMIM:603731) which are involved in regulating protein stability during G1 and G2 cell cycle phase transitions; by homology, UBC-3 is likely required for covalent attachment of ubiquitin to select target proteins to facilitate their degradation; however, as loss of UBC-3 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UBC-3 in C. elegans development and/or behavior is not yet known. |
Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (I:1699828..1700899)
Transcript overlap: 405 nt |
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Sliding Window |
Raw score: 342
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "Y71G12B.15" Links |
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JA:Y71G12A_187.a Phenotypes |
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Phenotype |
WT
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JA:Y71G12A_187.a Experiment Details |
Ace View |
Laboratory |
JA |
RNAi Reagent & Type |
sjj_Y71G12A_187.a (PCR_reagent) |
Reference |
Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...." |
Date |
2000-11-16 |
Gene Plot of Y71G12B.15 |
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