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RNAi Experiment: JA:Y75B12B.5 Ace View of JA:Y75B12B.5
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y75B12B.5 (cyn-3)
Description of "Y75B12B.5"  cyp-3 encodes an abundantly expressed cyclophilin A isoform with peptidyl-prolyl isomerase activity in vitro, which closely resembles the prototypical CypA and is thus likely to be a member of the cytosolic CsA-binding cyclophilin subfamily; cyp-3 is exclusively expressed in the single anterior excretory cell, and is dispensable for viability and gross morphology in mass RNAi screens.
KOG Annotation  Cyclophilin type peptidyl-prolyl cis-trans isomerase
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (V:15192344..15193433)
Transcript overlap: 561 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 498
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.776
Wormbase (BLAST) RNAi primary
External "Y75B12B.5" Links  Wormbase NCBI
Gene Inhibited  Y75B12B.2 (cyn-7)
Description of "Y75B12B.2"  cyp-7 encodes a cyclophilin A isoform; while not tested peptidyl-prolyl isomerase activity in vitro, it is very similar to CYP-3 and closely resembles the prototypical CypA, and is therefore likely to be a member of the cytosolic CsA-binding cyclophilin subfamily; CYP-7 was required for embryonic viability in one set of mass RNAi assays.
KOG Annotation  Cyclophilin type peptidyl-prolyl cis-trans isomerase
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 143
Relative score: 0.288 (Best raw score= for Gene )
Specificity index: 0.224
Wormbase (BLAST) RNAi primary
External "Y75B12B.2" Links  Wormbase NCBI
JA:Y75B12B.5 Phenotypes Help with Phenotypes
Phenotype  WT
JA:Y75B12B.5 Experiment Details Ace View
Laboratory  JA
RNAi Reagent & Type  sjj_Y75B12B.5 (PCR_reagent)
Reference  Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...."
Date  2003-1-10
Gene Plot of Y75B12B.5 Browse using GBrowse
Gene Graph
Gene Plot of Y75B12B.2 Browse using GBrowse
Gene Graph