RNAi Experiment: JA:ZK1248.6 |
Ace View of JA:ZK1248.6
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Genes Inhibited |
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Gene Inhibited |
ZK1248.6 (msp-64) |
Description of "ZK1248.6" |
msp-64 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (II:5809343..5810367)
Transcript overlap: 419 nt |
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Sliding Window |
Raw score: 377
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.35 |
Wormbase (BLAST) |
RNAi primary |
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External "ZK1248.6" Links |
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Gene Inhibited |
K05F1.2 (msp-142) |
Description of "K05F1.2" |
msp-142 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 168
Relative score: 0.446 (Best raw score= for Gene )
Specificity index: 0.156 |
Wormbase (BLAST) |
RNAi secondary |
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External "K05F1.2" Links |
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Gene Inhibited |
ZK354.1 (msp-65) |
Description of "ZK354.1" |
msp-65 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 59 |
Wormbase (BLAST) |
RNAi secondary |
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External "ZK354.1" Links |
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Gene Inhibited |
ZK1248.17 |
Description of "ZK1248.17" |
Associated GO Term : structural molecule activity |
Evidence for Inhibition |
Sliding Window |
Raw score: 102
Relative score: 0.271 (Best raw score= for Gene )
Specificity index: 0.095 |
Wormbase (BLAST) |
RNAi secondary |
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External "ZK1248.17" Links |
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Gene Inhibited |
F36H12.7 (msp-19) |
Description of "F36H12.7" |
msp-19 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-19 has a homolog in C. briggsae as predicted by the Wobble Aware Bulk Aligner (WABA); the msp gene family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 62
Relative score: 0.164 (Best raw score= for Gene )
Specificity index: 0.058 |
Wormbase (BLAST) |
RNAi secondary |
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External "F36H12.7" Links |
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Gene Inhibited |
ZK354.10 (msp-58) |
Description of "ZK354.10" |
msp-58 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 59 |
Wormbase (BLAST) |
RNAi secondary |
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External "ZK354.10" Links |
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Gene Inhibited |
C34F11.4 (msp-50) |
Description of "C34F11.4" |
msp-50 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 71
Relative score: 0.188 (Best raw score= for Gene )
Specificity index: 0.066 |
Wormbase (BLAST) |
RNAi secondary |
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External "C34F11.4" Links |
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Gene Inhibited |
K05F1.7 (msp-63) |
Description of "K05F1.7" |
msp-63 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 144
Relative score: 0.382 (Best raw score= for Gene )
Specificity index: 0.134 |
Wormbase (BLAST) |
RNAi secondary |
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External "K05F1.7" Links |
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Gene Inhibited |
ZK1248.4 |
Description of "ZK1248.4" |
Associated GO Term : structural molecule activity |
Evidence for Inhibition |
Sliding Window |
Raw score: 74
Relative score: 0.196 (Best raw score= for Gene )
Specificity index: 0.069 |
Wormbase (BLAST) |
RNAi secondary |
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External "ZK1248.4" Links |
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Gene Inhibited |
ZK354.4 (msp-113) |
Description of "ZK354.4" |
msp-113 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-113 has a C. briggsae homolog as detected by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; the msp-113 promoter region contains two conserved cis elements that are recognition sites for elt-1, a gene that encodes a homolog of the vertebrate GATA transcription factor family; this suggests that a MSP protein is a potential target for ELT-1 in the germ-line; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 59 |
Wormbase (BLAST) |
RNAi secondary |
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External "ZK354.4" Links |
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Gene Inhibited |
R13H9.4 (msp-53) |
Description of "R13H9.4" |
msp-53 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-53 has a C. briggsae homolog as identified by the Wobble Aware Bulk Aligner (WABA); the MSP family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. |
Evidence for Inhibition |
Sliding Window |
Raw score: 59 |
Wormbase (BLAST) |
RNAi secondary |
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External "R13H9.4" Links |
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Gene Inhibited |
ZK354.11 (msp-59) |
Description of "ZK354.11" |
msp-59 encodes a member of the major sperm protein family. |
Evidence for Inhibition |
Sliding Window |
Raw score: 59 |
Wormbase (BLAST) |
RNAi secondary |
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External "ZK354.11" Links |
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Gene Inhibited |
R05F9.13 (msp-31) |
Description of "R05F9.13" |
msp-31 encodes a member of the major sperm protein family; msp-31 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); expression is enriched in sperm. |
Evidence for Inhibition |
Sliding Window |
Raw score: 78
Relative score: 0.207 (Best raw score= for Gene )
Specificity index: 0.072 |
Wormbase (BLAST) |
RNAi secondary |
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External "R05F9.13" Links |
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JA:ZK1248.6 Phenotypes |
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Phenotype |
WT
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JA:ZK1248.6 Experiment Details |
Ace View |
Laboratory |
JA |
RNAi Reagent & Type |
sjj_ZK1248.6 (PCR_reagent) |
Reference |
Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." |
Date |
2003-1-10 |
Gene Plot of K05F1.2 |
Browse using GBrowse
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Gene Plot of ZK354.1 |
Browse using GBrowse
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Gene Plot of ZK1248.17 |
Browse using GBrowse
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Gene Plot of ZK1248.6 |
Browse using GBrowse
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Gene Plot of F36H12.7 |
Browse using GBrowse
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Gene Plot of ZK354.10 |
Browse using GBrowse
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Gene Plot of C34F11.4 |
Browse using GBrowse
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Gene Plot of K05F1.7 |
Browse using GBrowse
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Gene Plot of ZK1248.4 |
Browse using GBrowse
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Gene Plot of R13H9.4 |
Browse using GBrowse
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Gene Plot of ZK354.4 |
Browse using GBrowse
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Gene Plot of R05F9.13 |
Browse using GBrowse
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Gene Plot of ZK354.11 |
Browse using GBrowse
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