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RNAi Experiment: JA:ZK524.2 Ace View of JA:ZK524.2
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  ZK524.2 (unc-13)
Description of "ZK524.2"  unc-13 encodes at least five protein isoforms that regulate neurotransmitter release by altering the conformation of syntaxin; UNC-13 proteins are required for normal pharyngeal pumping and thrashing in liquid, normally short lifespan, normally large brood sizes, and full adult body sizes; UNC-13 proteins have orthologs in vertebrates and Drosophila; UNC-13 proteins are complex, with multiple C2, phorbol ester-binding, and DUF1041 domains; UNC-13 protein form is localized to most or all synapses; many of the unc-13 mutant alleles with viable phenotypes are transcript-specific, while homozygotes with an unc-13 null (deletion) allele die as paralyzed first-stage larvae.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:7451784..7452950)
Transcript overlap: 879 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 816
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "ZK524.2" Links  Wormbase NCBI
JA:ZK524.2 Phenotypes Help with Phenotypes
Phenotype  WT
JA:ZK524.2 Experiment Details Ace View
Laboratory  JA
RNAi Reagent & Type  sjj_ZK524.2 (PCR_reagent)
Reference  Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...."
Date  2000-11-16
Gene Plot of ZK524.2 Browse using GBrowse
Gene Graph