RNAi Experiment: JA:ZK617.1 |
Ace View of JA:ZK617.1
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Genes Inhibited |
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Gene Inhibited |
ZK617.1 (unc-22) |
Description of "ZK617.1" |
unc-22 encodes twitchin, a giant intracellular protein with multiple fibronectin- and immunoglobulin-like domains and a single protein kinase domain that is homologous to titin (OMIM:188840); UNC-22 is required in muscle for regulation of the actomyosin contraction-relaxation cycle and for maintenance of normal muscle morphology; UNC-22 associates with myosin and is localized to A-bands; in vitro, UNC-22 can phosphorylate myosin light-chain peptides and can undergo autophosphorylation. |
KOG Annotation  |
Projectin/twitchin and related proteins
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (IV:11987289..11988439)
Transcript overlap: 1151 nt |
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Sliding Window |
Raw score: 1151
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "ZK617.1" Links |
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JA:ZK617.1 Phenotypes |
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Adult |
Unc
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JA:ZK617.1 Experiment Details |
Ace View |
Laboratory |
JA |
RNAi Reagent & Type |
sjj_ZK617.1 (PCR_reagent) |
Reference |
Kamath RS et al. (2003) Nature "Systemic functional analysis of the Caenorhabditis elegans genome using ...." |
Date |
2003-1-10 |
Gene Plot of ZK617.1 |
Browse using GBrowse
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