RNAi Experiment: JA:ZK909.1 |
Ace View of JA:ZK909.1
|
Genes Inhibited |
|
Gene Inhibited |
ZK909.2 (kin-1) |
Description of "ZK909.2" |
kin-1 encodes multiple isoforms of a serine/threonine protein kinase that is orthologous to cAMP-dependent protein kinase (protein kinase A or PKA) catalytic subunits; KIN-1 is able to phosphorylate histone H2B in vitro and is associated with both particulate (~65%) and cytosolic (35%) cellular fractions; KIN-1 is expressed at low levels during embryogenesis, but its expression level increases in late embryogenesis, whereupon KIN-1 expression remains relatively high throughout larval and adult development; kin-1 mRNA levels, however, are fairly constant throughout development, suggesting that KIN-1 expression is regulated post-transcriptionally; as loss of kin-1 activity via large-scale RNAi screens results in no obvious defects, the precise role of kin-1 in C. elegans development and/or behavior is not yet known. |
Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (I:14945836..14947329)
Transcript overlap: 952 nt |
|
Sliding Window |
Raw score: 931
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
|
External "ZK909.2" Links |
|
JA:ZK909.1 Phenotypes |
|
|
Phenotype |
WT
|
JA:ZK909.1 Experiment Details |
Ace View |
Laboratory |
JA |
RNAi Reagent & Type |
sjj_ZK909.1 (PCR_reagent) |
Reference |
Fraser AG et al. (2000) Nature "Functional genomic analysis of C. elegans chromosome I by systematic RNA ...." |
Date |
2000-11-16 |
Gene Plot of ZK909.2 |
Browse using GBrowse
|
|