Link to W06F12.1dLink to W06F12.1aLink to W06F12.1e.1Link to W06F12.1b.1Link to W06F12.1b.2Link to W06F12.1e.2Link to W06F12.1cRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
RNAi Experiment: JN:yk499g10 Ace View of JN:yk499g10
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  W06F12.1 (lit-1)
Description of "W06F12.1"  lit-1 encodes a serine threonine protein kinase homolog related to the Drosophila protein Nemo that is required for embryonic viability, plays a central role in controlling the asymmetry of cell divisions during embryogenesis, and affects EMS, MS, and C lineages; acts downstream of mom-2 with respect to polarity defects and mediates larval cell fate decisions that involve POP-1, and is expressed in most embryonic and larval cells.
Evidence for Inhibition 
Sliding Window Raw score: 1720
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "W06F12.1" Links  Wormbase NCBI
JN:yk499g10 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
JN:yk499g10 Experiment Details Ace View
Laboratory  JN
RNAi Reagent & Type  yk499g10 (cDNA_reagent)
Strain  [cgc4769]peIs1
Remark  co-injectin of gfp dsRNA as a control
Reference  Hanazawa M et al. (2001) Proceedings of the National Academy of Sciences USA "Use of cDNA subtraction and RNA interference screens in combination reveals ...."
Delivery Method  Injection
Date  2001-7-17
Gene Plot of W06F12.1 Browse using GBrowse
Gene Graph