Ace View of KK:SP_5H5 | ||||
Gene Inhibited | F39H11.5 (pbs-7) | |||
Description of "F39H11.5" | pbs-7 encodes a B-type subunit of the 26S proteasome's 20S protease core particle; by homology, PBS-7 is predicted to function in ATP/ubiquitin-dependent nonlysosomal protein degradation; loss of pbs-7 activity via large-scale RNAi screens indicates that, in C. elegans, PBS-7 is required for normal movement and for embryonic, germline, and larval development. | |||
KOG Annotation  | 20S proteasome, regulatory subunit beta type PSMB4/PRE4 |
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Evidence for Inhibition |
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External "F39H11.5" Links | ||||
Embryonic | Emb Penetrance 80 - 100 % | |||
Adult | Ste Egg production ceases in injected animal |
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Phenotype | Catastrophic one-cell arrest |
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Movies/Stacks/Images | ||||
Laboratory | KK | |||
RNAi Reagent & Type | SP5H5 (cDNA_reagent) | |||
Reference | Piano F et al. (2000) Current Biology "RNAi analysis of genes expressed in the ovary of Caenorhabditis ...." | |||
Delivery Method | Injection | |||
Date | 2000-12-08 | |||
Gene Plot of F39H11.5 | ||||