| RNAi Experiment: MV_SV:mv_AAA18956 |
Ace View of MV_SV:mv_AAA18956
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| Genes Inhibited |
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| Gene Inhibited |
F43C1.2 (mpk-1) |
| Description of "F43C1.2" |
mpk-1 encodes a mitogen-activated protein (MAP) kinase that acts in the vulval precursor cells to affect LET-60(Ras)-mediated induction of vulval cell fates, and also affects larval viability, morphology of the male spicules, and acts in combination with mek-2 to permit germ cell exit from the pachytene stage of first meiotic prophase; both LIN-1 and LIN-31 act genetically downstream of mpk-1 with respect to vulval induction, and LIN-1 and LIN-31 are substrates for MPK-1 in vitro. |
| KOG Annotation |
Mitogen-activated protein kinase
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|
| Evidence for Inhibition |
| Sliding Window |
Raw score: 1185
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
| Wormbase (BLAST) |
RNAi primary |
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| External "F43C1.2" Links |
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| MV_SV:mv_AAA18956 Phenotypes |
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| Larval |
Let
penetrance is less than 90%
|
| Adult |
Pvl
penetrance is less than 90%
|
| Phenotype |
Unclassified
reduced brood size
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| MV_SV:mv_AAA18956 Experiment Details |
Ace View |
| Laboratory |
MV |
| RNAi Reagent & Type |
mv_AAA18956 (ORFeome_reagent) |
| Remark |
bacterial-feeding RNAi began at the L1 larval stage |
| Reference |
Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...." |
| Delivery Method |
Bacterial_feeding |
| Date |
2004-9-01 |
| Gene Plot of F43C1.2 |
Browse using GBrowse
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