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RNAi Experiment: MV_SV:mv_AAA28066 Ace View of MV_SV:mv_AAA28066
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T27E4.8 (hsp-16.1)
Description of "T27E4.8"  hsp-16.1 encodes a 16-kD heat shock protein (HSP) that is a member of the hsp16/hsp20/alphaB-crystallin (HSP16) family of heat shock proteins, and that is identical to the protein encoded by hsp-16.11; an hsp-16.1 reporter fusion, expressed broadly but most strongly in muscle and hypodermis, is induced solely in response to heat shock or other environmental stresses; expression is detectable in somatic tissues in post-gastrulation embryos, all larval stages, and in adults; HSP-16.1 is likely to function as a passive ligand temporarily preventing unfolded proteins from aggregating.
KOG Annotation  Alpha crystallins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 393
Specificity index: 0.5
Wormbase (BLAST) RNAi primary
External "T27E4.8" Links  Wormbase NCBI
Gene Inhibited  T27E4.2 (hsp-16.11)
Description of "T27E4.2"  hsp-16.11 encodes a 16-kD heat shock protein (HSP) that is a member of the hsp16/hsp20/alphaB-crystallin (HSP16) family of heat shock proteins, and that is identical to the protein encoded by hsp-16.1; hsp-16.11 expression is induced in response to heat shock or other environmental stresses; HSP-16.11 is likely to function as passive ligand temporarily preventing unfolded proteins from aggregating; HSP-16.11 has been shown to interact with intracellular human beta amyloid peptide, a primary component of the extracellular plaques found in Alzheimer's disease.
Evidence for Inhibition 
Sliding Window Raw score: 393
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.5
Wormbase (BLAST) RNAi primary
External "T27E4.2" Links  Wormbase NCBI
MV_SV:mv_AAA28066 Phenotypes Help with Phenotypes
Phenotype  WTRNAi did not cause viable post-embryonic phenotype
MV_SV:mv_AAA28066 Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_AAA28066 (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of T27E4.8 Browse using GBrowse
Gene Graph
Gene Plot of T27E4.2 Browse using GBrowse
Gene Graph