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RNAi Experiment: MV_SV:mv_AAA28071 Ace View of MV_SV:mv_AAA28071
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y46H3A.3 (hsp-16.2)
Description of "Y46H3A.3"  hsp-16.2 encodes a 16-kD heat shock protein (HSP) that is a member of the hsp16/hsp20/alphaB-crystallin (HSP16) family of heat shock proteins; hsp-16.2 expression, strongest in intestine and pharynx, is induced in response to heat shock or other environmental stresses; HSP-16.2 has been shown to interact with intracellular human beta amyloid peptide, a primary component of the extracellular plaques found in Alzheimer's disease; HSP-16.2 is likely to function as a passive ligand temporarily preventing unfolded proteins from aggregating.
KOG Annotation  Alpha crystallins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 372
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y46H3A.3" Links  Wormbase NCBI
MV_SV:mv_AAA28071 Phenotypes Help with Phenotypes
Phenotype  WTRNAi did not cause viable post-embryonic phenotype
MV_SV:mv_AAA28071 Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_AAA28071 (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of Y46H3A.3 Browse using GBrowse
Gene Graph