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RNAi Experiment: MV_SV:mv_AAC47125 Ace View of MV_SV:mv_AAC47125
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y75B12B.5 (cyn-3)
Description of "Y75B12B.5"  cyp-3 encodes an abundantly expressed cyclophilin A isoform with peptidyl-prolyl isomerase activity in vitro, which closely resembles the prototypical CypA and is thus likely to be a member of the cytosolic CsA-binding cyclophilin subfamily; cyp-3 is exclusively expressed in the single anterior excretory cell, and is dispensable for viability and gross morphology in mass RNAi screens.
KOG Annotation  Cyclophilin type peptidyl-prolyl cis-trans isomerase
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 164
Relative score: 0.402 (Best raw score= for Gene )
Specificity index: 0.287
Wormbase (BLAST) RNAi primary
External "Y75B12B.5" Links  Wormbase NCBI
Gene Inhibited  Y75B12B.2 (cyn-7)
Description of "Y75B12B.2"  cyp-7 encodes a cyclophilin A isoform; while not tested peptidyl-prolyl isomerase activity in vitro, it is very similar to CYP-3 and closely resembles the prototypical CypA, and is therefore likely to be a member of the cytosolic CsA-binding cyclophilin subfamily; CYP-7 was required for embryonic viability in one set of mass RNAi assays.
KOG Annotation  Cyclophilin type peptidyl-prolyl cis-trans isomerase
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 408
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.713
Wormbase (BLAST) RNAi primary
External "Y75B12B.2" Links  Wormbase NCBI
MV_SV:mv_AAC47125 Phenotypes Help with Phenotypes
Phenotype  WTRNAi did not cause viable post-embryonic phenotype
MV_SV:mv_AAC47125 Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_AAC47125 (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of Y75B12B.5 Browse using GBrowse
Gene Graph
Gene Plot of Y75B12B.2 Browse using GBrowse
Gene Graph