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RNAi Experiment: MV_SV:mv_AAD34863 Ace View of MV_SV:mv_AAD34863
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T20H4.5
Description of "T20H4.5"  The T20H4.5 gene encodes an ortholog of the human gene NADH DEHYDROGENASE-UBIQUINONE FE-S PROTEIN 8 23 KDA SUBUNIT; MITOCHONDRIAL COMPLEX I TYKY SUBUNIT (NDUFS8; OMIM:602141), which when mutated leads to Leigh syndrome (OMIM:256000); the T20H4.5 protein is predicted to be mitochondrial with 52% accuracy.
KOG Annotation  NADH:ubiquinone oxidoreductase, NDUFS8/23 kDa subunit
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 552
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "T20H4.5" Links  Wormbase NCBI
MV_SV:mv_AAD34863 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Phenotype  Unclassified reduced brood size
MV_SV:mv_AAD34863 Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_AAD34863 (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of T20H4.5 Browse using GBrowse
Gene Graph