RNAi Experiment: MV_SV:mv_C05D11.3 |
Ace View of MV_SV:mv_C05D11.3
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Genes Inhibited |
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Gene Inhibited |
C05D11.3 |
Description of "C05D11.3" |
C05D11.3 encodes an ortholog of APACD (ATP binding protein associated with cell differentiation) conserved in eukaryotes; C05D11.3 has a thioredoxin-like domain, probably lacking catalytic activity; mouse APACD is both cytoplasmic and nuclear, often localized to centrosomes and midbody; C05D11.3 is expressed in all developmental stages, preferentially in neurons and vulva; C05D11.3 is required for normal mitotic spindle formation, pronuclear migration and nuclear-centrosome rotation. |
KOG Annotation  |
ATP binding protein
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Evidence for Inhibition |
Sliding Window |
Raw score: 561
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "C05D11.3" Links |
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MV_SV:mv_C05D11.3 Phenotypes |
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Embryonic |
Emb Penetrance None reported |
Adult |
Pvl
penetrance is less than 90%
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Phenotype |
Bli Unclassified
reduced brood size
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MV_SV:mv_C05D11.3 Experiment Details |
Ace View |
Laboratory |
MV |
RNAi Reagent & Type |
mv_C05D11.3 (ORFeome_reagent) |
Remark |
bacterial-feeding RNAi began at the L1 larval stage |
Reference |
Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...." |
Delivery Method |
Bacterial_feeding |
Date |
2004-9-01 |
Gene Plot of C05D11.3 |
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