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RNAi Experiment: MV_SV:mv_C25A11.3 Ace View of MV_SV:mv_C25A11.3
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C25A11.4 (ajm-1)
Description of "C25A11.4"  ajm-1 encodes a member of the apical junction molecule class that is required for correct elongation of the C. elegans embryo; AJM-1 contains a coiled-coil motif; AJM-1 binds DLG-1 in vitro, in yeast two-hybrid assays, and in vivo; AJM-1 is mislocalized in a dlg-1(RNAi) background; LET-413 is required for rapid confinement of DLG-1 and AJM-1 to a narrow apical region in C. elegans epithelia; CLC-1 colocalizes with AJM-1; vab-9 mutations enhance the adhesion defects of ajm-1 mutants; ajm-1 is expressed at the apical borders of all epithelia.
Evidence for Inhibition 
Sliding Window Raw score: 862
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C25A11.4" Links  Wormbase NCBI
MV_SV:mv_C25A11.3 Phenotypes Help with Phenotypes
Phenotype  WTRNAi did not cause viable post-embryonic phenotype
MV_SV:mv_C25A11.3 Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_C25A11.3 (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of C25A11.4 Browse using GBrowse
Gene Graph