RNAi Experiment: MV_SV:mv_C29F9.7 |
Ace View of MV_SV:mv_C29F9.7
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Genes Inhibited |
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Gene Inhibited |
C29F9.7 (pat-4) |
Description of "C29F9.7" |
The pat-4 gene encodes a serine/threonine kinase orthologous to human integrin-linked kinase (ILK, OMIM:602366) and is required for formation of integrin-mediated muscle cell attachments during embryogenesis; PAT-4 probably functions as an adaptor molecule and localizes to dense bodies and M lines; PAT-4 forms a ternary complex with PAT-6/actopaxin and UNC-112, and requires UNC-112, UNC-52/perlecan, PAT-2/alpha integrin, and PAT-3/beta integrin for proper localization to newly forming integrin adhesion complexes. |
KOG Annotation  |
Integrin-linked kinase
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Evidence for Inhibition |
Sliding Window |
Raw score: 1230
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "C29F9.7" Links |
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MV_SV:mv_C29F9.7 Phenotypes |
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Larval |
Let
penetrance is less than 90%
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Adult |
Ste Unc
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MV_SV:mv_C29F9.7 Experiment Details |
Ace View |
Laboratory |
MV |
RNAi Reagent & Type |
mv_C29F9.7 (ORFeome_reagent) |
Remark |
bacterial-feeding RNAi began at the L1 larval stage |
Reference |
Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...." |
Delivery Method |
Bacterial_feeding |
Date |
2004-9-01 |
Gene Plot of C29F9.7 |
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