RNAi Experiment: MV_SV:mv_C35B1.1 |
Ace View of MV_SV:mv_C35B1.1
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Genes Inhibited |
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Gene Inhibited |
C35B1.1 (ubc-1) |
Description of "C35B1.1" |
ubc-1 encodes an E2 ubiquitin-conjugating enzyme that contains a novel 40 amino acid C-terminal tail, and is homologous to Saccharomyces cerevisiae RAD6/UBC2 which is involved in DNA repair; although loss of UBC-1 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, UBC-1 is able to complement the DNA repair defects of a Saccharomyces cerevisiae rad6 null mutant, suggesting that UBC-1 can function in the DNA repair pathway; ubc-1 mRNA is detectable in embryos. |
KOG Annotation  |
Ubiquitin-protein ligase
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Evidence for Inhibition |
Sliding Window |
Raw score: 513
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "C35B1.1" Links |
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MV_SV:mv_C35B1.1 Phenotypes |
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Larval |
Let
penetrance is less than 90% Lva
penetrance is less than 90%
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Adult |
Sck
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Phenotype |
Unclassified
reduced brood size
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MV_SV:mv_C35B1.1 Experiment Details |
Ace View |
Laboratory |
MV |
RNAi Reagent & Type |
mv_C35B1.1 (ORFeome_reagent) |
Remark |
bacterial-feeding RNAi began at the L1 larval stage |
Reference |
Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...." |
Delivery Method |
Bacterial_feeding |
Date |
2004-9-01 |
Gene Plot of C35B1.1 |
Browse using GBrowse
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