Link to C35B1.2aLink to C35B1.1.2Link to C35B1.1.1RNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
RNAi Experiment: MV_SV:mv_C35B1.1 Ace View of MV_SV:mv_C35B1.1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C35B1.1 (ubc-1)
Description of "C35B1.1"  ubc-1 encodes an E2 ubiquitin-conjugating enzyme that contains a novel 40 amino acid C-terminal tail, and is homologous to Saccharomyces cerevisiae RAD6/UBC2 which is involved in DNA repair; although loss of UBC-1 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, UBC-1 is able to complement the DNA repair defects of a Saccharomyces cerevisiae rad6 null mutant, suggesting that UBC-1 can function in the DNA repair pathway; ubc-1 mRNA is detectable in embryos.
KOG Annotation  Ubiquitin-protein ligase
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 513
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C35B1.1" Links  Wormbase NCBI
MV_SV:mv_C35B1.1 Phenotypes Help with Phenotypes
Larval  Let penetrance is less than 90%
Lva penetrance is less than 90%
Adult  Sck
Phenotype  Unclassified reduced brood size
MV_SV:mv_C35B1.1 Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_C35B1.1 (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of C35B1.1 Browse using GBrowse
Gene Graph