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RNAi Experiment: MV_SV:mv_C37C3.6a Ace View of MV_SV:mv_C37C3.6a
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  D2045.1 (atx-2)
Description of "D2045.1"  atx-2 is required for early embryonic patterning; it encodes an ortholog of human ataxin-2, which when mutated leads to spinocerebellar ataxia 2 (SCA2; OMIM:183090).
Evidence for Inhibition 
Sliding Window Raw score: 338
Relative score: 0.084 (Best raw score= for Gene )
Specificity index: 0.077
External "D2045.1" Links  Wormbase NCBI
Gene Inhibited  C37C3.6 (ppn-1)
Description of "C37C3.6"  C37C3.6 encodes three isoforms of a large, novel multidomain glycoprotein orthologous to thrombospondin from Haemonchus contortus, papilin from D. melanogaster, and lacunin from Manduca sexta; the N-terminal region of C37C3.6 proteins have a domain set also found in the C-terminal region of ADAMTS matrix-associated metalloproteinases; C37C3.6 is generally required for normal cell arrangements, being required in embryos for viability and normal hypodermal enclosure, and in L1 larvae for normal excretory canal function.
Evidence for Inhibition 
Sliding Window Raw score: 4443
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.923
Wormbase (BLAST) RNAi primary
External "C37C3.6" Links  Wormbase NCBI
MV_SV:mv_C37C3.6a Phenotypes Help with Phenotypes
Larval  Let penetrance is less than 90%
Adult  Pvl penetrance is less than 90%
Sck
Ste
Phenotype  Bli penetrance is less than 90%
MV_SV:mv_C37C3.6a Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_C37C3.6a (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of D2045.1 Browse using GBrowse
Gene Graph
Gene Plot of C37C3.6 Browse using GBrowse
Gene Graph