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RNAi Experiment: MV_SV:mv_CAA04171 Ace View of MV_SV:mv_CAA04171
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F11A5.10 (glc-1)
Description of "F11A5.10"  glc-1 encodes the alpha subunit of a glutamate-gated chloride channel and forms a functional channel in Xenopus oocytes; mutations genetically interact with avr-14 and avr-15 mutations such that triple mutants exhibit high level resistance to ivermectin.
KOG Annotation  Ligand-gated ion channel
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 64
Relative score: 0.041 (Best raw score= for Gene )
Specificity index: 0.04
Wormbase (BLAST) RNAi secondary
External "F11A5.10" Links  Wormbase NCBI
Gene Inhibited  R11G10.1 (avr-15)
Description of "R11G10.1"  avr-15 encodes, via alternative splicing, two glutamate-gated chloride channel subunit homologs; these proteins mediate fast inhibitory glutamatergic neuromuscular transmission, as well as ivermectin sensitivity, and are required for normal pharyngeal function.
KOG Annotation  Ligand-gated ion channel
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 1761
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.96
Wormbase (BLAST) RNAi primary
External "R11G10.1" Links  Wormbase NCBI
MV_SV:mv_CAA04171 Phenotypes Help with Phenotypes
Phenotype  WTRNAi did not cause viable post-embryonic phenotype
MV_SV:mv_CAA04171 Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_CAA04171 (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of R11G10.1 Browse using GBrowse
Gene Graph
Gene Plot of F11A5.10 Browse using GBrowse
Gene Graph