RNAi Experiment: MV_SV:mv_CAA09234 |
Ace View of MV_SV:mv_CAA09234
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Genes Inhibited |
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Gene Inhibited |
C05D11.4 (let-756) |
Description of "C05D11.4" |
let-756 encodes an fibroblast growth factor (FGF)-like ligand that is required for progression through early larval development; LET-756 is expressed from late embryogenesis to adulthood, with a peak of expression in larvae; with EGL-17, LET-756 is redundantly required to activate EGL-15/FGFR, which in turn activates protein degradation in adult muscle cells; homozygotes for partial loss-of-function alleles are small, clear, and scrawny, but viable, while those for a null allele arrest in early larval development. |
KOG Annotation  |
Fibroblast growth factor
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Evidence for Inhibition |
Sliding Window |
Raw score: 1107
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "C05D11.4" Links |
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MV_SV:mv_CAA09234 Phenotypes |
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Phenotype |
WTRNAi did not cause viable post-embryonic phenotype
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MV_SV:mv_CAA09234 Experiment Details |
Ace View |
Laboratory |
MV |
RNAi Reagent & Type |
mv_CAA09234 (ORFeome_reagent) |
Remark |
bacterial-feeding RNAi began at the L1 larval stage |
Reference |
Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...." |
Delivery Method |
Bacterial_feeding |
Date |
2004-9-01 |
Gene Plot of C05D11.4 |
Browse using GBrowse
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