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RNAi Experiment: MV_SV:mv_CAA09234 Ace View of MV_SV:mv_CAA09234
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C05D11.4 (let-756)
Description of "C05D11.4"  let-756 encodes an fibroblast growth factor (FGF)-like ligand that is required for progression through early larval development; LET-756 is expressed from late embryogenesis to adulthood, with a peak of expression in larvae; with EGL-17, LET-756 is redundantly required to activate EGL-15/FGFR, which in turn activates protein degradation in adult muscle cells; homozygotes for partial loss-of-function alleles are small, clear, and scrawny, but viable, while those for a null allele arrest in early larval development.
KOG Annotation  Fibroblast growth factor
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 1107
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C05D11.4" Links  Wormbase NCBI
MV_SV:mv_CAA09234 Phenotypes Help with Phenotypes
Phenotype  WTRNAi did not cause viable post-embryonic phenotype
MV_SV:mv_CAA09234 Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_CAA09234 (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of C05D11.4 Browse using GBrowse
Gene Graph