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RNAi Experiment: MV_SV:mv_F09C12.7 Ace View of MV_SV:mv_F09C12.7
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F09C12.7 (msp-74)
Description of "F09C12.7"  msp-74 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
Evidence for Inhibition 
Sliding Window Raw score: 189
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F09C12.7" Links  Wormbase NCBI
MV_SV:mv_F09C12.7 Phenotypes Help with Phenotypes
Phenotype  WTRNAi did not cause viable post-embryonic phenotype
MV_SV:mv_F09C12.7 Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_F09C12.7 (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of F09C12.7 Browse using GBrowse
Gene Graph