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RNAi Experiment: MV_SV:mv_F18A1.5 Ace View of MV_SV:mv_F18A1.5
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F18A1.5
Description of "F18A1.5"  F18A1.5 encodes the C. elegans ortholog of the replication protein A (RPA) large subunit; by homology, the F18A1.5 gene product is predicted to function as a DNA binding and oligonucleotide oligosaccharide binding (OB) protein that is required for DNA replication, repair, and recombination; large-scale RNAi screens indicate that the product of F18A1.5 is essential for embryonic development, and that in yeast two-hybrid assays interacts with the product of M04F3.1, the RPA medium subunit; in situ hybridization studies indicate that F18A1.5 transcripts are expressed in germ cells.
KOG Annotation  Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 1776
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F18A1.5" Links  Wormbase NCBI
MV_SV:mv_F18A1.5 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
MV_SV:mv_F18A1.5 Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_F18A1.5 (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of F18A1.5 Browse using GBrowse
Gene Graph