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RNAi Experiment: MV_SV:mv_F18A12.5 Ace View of MV_SV:mv_F18A12.5
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F18A12.5
Description of "F18A12.5"  F18A12.5 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; F18A12.5 has no clear orthologs in other organisms.
KOG Annotation  M13 family peptidase
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 1785
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F18A12.5" Links  Wormbase NCBI
MV_SV:mv_F18A12.5 Phenotypes Help with Phenotypes
Phenotype  WTRNAi did not cause viable post-embryonic phenotype
MV_SV:mv_F18A12.5 Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_F18A12.5 (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of F18A12.5 Browse using GBrowse
Gene Graph