RNAi Experiment: MV_SV:mv_F32A7.6 |
Ace View of MV_SV:mv_F32A7.6
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Genes Inhibited |
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Gene Inhibited |
F32A7.6 (aex-5) |
Description of "F32A7.6" |
an ortholog of calcium-dependent serine endoproteinases, the kex2/subtilisin-like proprotein convertase that affects defecation cycle and anterior body contractions; and is expressed in all muscle cells except pharyngeal muscles. |
KOG Annotation  |
Subtilisin-like proprotein convertase
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Evidence for Inhibition |
Sliding Window |
Raw score: 1443
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.81 |
Wormbase (BLAST) |
RNAi primary |
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External "F32A7.6" Links |
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Gene Inhibited |
F11C3.3 (unc-54) |
Description of "F11C3.3" |
unc-54 encodes a muscle myosin class II heavy chain (MHC B); UNC-54 is the major myosin heavy chain expressed in C. elegans and is required for locomotion and egg-laying; in vivo and in vitro, UNC-54 interacts with ITR-1, an IP3 receptor, and this interaction may provide a link between calcium signaling and the muscle cytoskeleton; UNC-54 is a thick filament component that is expressed in multiple muscle cell classes including body wall, intestinal, anal depressor, and sphincter muscles as well as sex-specific muscles that develop postembryonically. |
KOG Annotation  |
Myosin class II heavy chain
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Evidence for Inhibition |
Sliding Window |
Raw score: 338
Relative score: 0.234 (Best raw score= for Gene )
Specificity index: 0.19 |
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External "F11C3.3" Links |
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MV_SV:mv_F32A7.6 Phenotypes |
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Embryonic |
Emb Penetrance None reported |
Larval |
Lva
penetrance is less than 90%
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MV_SV:mv_F32A7.6 Experiment Details |
Ace View |
Laboratory |
MV |
RNAi Reagent & Type |
mv_F32A7.6 (ORFeome_reagent) |
Remark |
bacterial-feeding RNAi began at the L1 larval stage |
Reference |
Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...." |
Delivery Method |
Bacterial_feeding |
Date |
2004-9-01 |
Gene Plot of F11C3.3 |
Browse using GBrowse
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Gene Plot of F32A7.6 |
Browse using GBrowse
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