Link to F46A9.4RNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentLink to F46A9.5.3Link to F46A9.5.2Link to F46A9.5.1geneMap
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RNAi Experiment: MV_SV:mv_F46A9.4 Ace View of MV_SV:mv_F46A9.4
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F46A9.4 (skr-2)
Description of "F46A9.4"  skr-2 encodes a homolog of Skp1 in S. cerevisiae, a core component of the SCF (Skp1p, Cullin, F-box) ubiquitin-ligase complex that facilitates ubiquitin-mediated protein degradation; SKR-2 is required for the restraint of cell proliferation, progression through the pachytene stage of meiosis, and the formation of bivalent chromosomes at diakinesis; SKR-2::GFP is detected exclusively in the intestine.
KOG Annotation  SCF ubiquitin ligase, Skp1 component
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 396
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F46A9.4" Links  Wormbase NCBI
MV_SV:mv_F46A9.4 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
MV_SV:mv_F46A9.4 Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_F46A9.4 (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of F46A9.4 Browse using GBrowse
Gene Graph