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RNAi Experiment: MV_SV:mv_F54A5.3a Ace View of MV_SV:mv_F54A5.3a
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F54A5.3
Description of "F54A5.3"  F54A5.3 encodes four proteins by multiple splicing, three of which are rather small (52-81 residues); however, one isoform (F54A5.3A, 316 residues) is a ortholog of vertebrate Shc proteins (e.g., p52/p46SHC and p66SHC); like its orthologs, F54A5.3A has a PTB and an SH2 domain in N- to C-terminal order; F54A5.3 has no obvious function in mass RNAi assays, but might be involved in RAS signal transduction or regulation of apoptosis.
KOG Annotation  Adaptor protein SHC and related proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 849
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F54A5.3" Links  Wormbase NCBI
MV_SV:mv_F54A5.3a Phenotypes Help with Phenotypes
Phenotype  WTRNAi did not cause viable post-embryonic phenotype
MV_SV:mv_F54A5.3a Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_F54A5.3a (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of F54A5.3 Browse using GBrowse
Gene Graph