Link to D2005.1RNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentLink to H15N14.1fLink to H15N14.1eLink to H15N14.1gLink to H15N14.1dLink to H15N14.1cgeneMap Link to H15N14.1cLink to H15N14.1dLink to H15N14.1eLink to H15N14.1gLink to H15N14.1fRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentLink to D2005.1geneMap
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RNAi Experiment: MV_SV:mv_H15N14.1b Ace View of MV_SV:mv_H15N14.1b
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  D2005.1
Description of "D2005.1"  Associated GO Term : RNA binding
Evidence for Inhibition 
Sliding Window Raw score: 907
Relative score: 0.468 (Best raw score= for Gene )
Specificity index: 0.319
Wormbase (BLAST) RNAi primary
External "D2005.1" Links  Wormbase NCBI
Gene Inhibited  H15N14.1 (adr-1)
Description of "H15N14.1"  adr-1 encodes, through alternative splicing, at least five isoforms of an adenosine deaminase that acts on RNA (ADAR); ADARs are RNA-editing enzymes that deaminate adenosines to create inosines in double-stranded RNA (dsRNA); adr-1 is expressed in embryos, most or all neurons (e.g., sensory neurons and cilia, the ventral nerve cord, motor neurons and interneurons) and in the developing (but not the adult) vulva; ADR-1 is required for ADAR activity in vivo, and for normal chemotaxis and vulval development; ADR-1 is also required (redundantly with ADR-2) to prevent the silencing of transgenes in somatic tissues by RNAi; ADR-1 (with ADR-2) may protect transgenic RNA from RNAi silencing by deaminating transgenic dsRNA; ADR-1 contains a glutamine/asparagine-rich domain, as well as two N-terminal double-stranded RNA-binding motifs.
Evidence for Inhibition 
Sliding Window Raw score: 2451
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.681
Wormbase (BLAST) RNAi primary
External "H15N14.1" Links  Wormbase NCBI
MV_SV:mv_H15N14.1b Phenotypes Help with Phenotypes
Larval  Lva phenotype observed among F1 progeny of treated animals
Phenotype  Unclassified reduced brood size
MV_SV:mv_H15N14.1b Experiment Details Ace View
Laboratory  MV
RNAi Reagent & Type  mv_H15N14.1b (ORFeome_reagent)
Remark  bacterial-feeding RNAi began at the L1 larval stage
Reference  Rual JF et al. (2004) Genome Res "Toward Improving Caenorhabditis elegans Phenome Mapping With an ORFeome-Based ...."
Delivery Method  Bacterial_feeding
Date  2004-9-01
Gene Plot of D2005.1 Browse using GBrowse
Gene Graph
Gene Plot of H15N14.1 Browse using GBrowse
Gene Graph